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Anas Bedraoui
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Anas Bedraoui

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Anas Bedraoui is a PhD candidate at FMS, UM6P, Morocco. He is a member of the Early Career Advisory Group at eLife, Cambridge, UK. Anas is interested in writing about science, research, and psychology. He loves the BLUWR community.
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The Real Reason Scientists Keep Going 7101

Anas Bedraoui, 3 mon.
They say the hardest thing to do is research. I mean science, right? But you have no idea how fun it actually is. When you're surrounded by a team of geniuses, each one bringing a different skill to the table, something magical happens. It's not a competition. It’s a quiet orchestra of minds. Everyone has their own zone of brilliance, and yet, everyone stays humble. Why? Because we all know that knowledge is never complete. You know things I don’t. I know things you don’t. And that’s perfectly fine. That’s how we grow. The beauty of research isn’t in instant success. It’s in the struggle. It’s in those long days and nights spent reading papers, writing code, running experiments, and getting nowhere. And then suddenly, a small insight hits you like lightning. A pattern. A correlation. A concept that no one else has connected before. That moment when something clicks—that’s the moment you realize why you do this. But let’s zoom out. In the grand scheme of things, your work is just one drop in an ocean of scientific progress. And still, that drop matters. You publish. Someone reads your paper, maybe in another continent. They find value in it. They cite it. You see the citation. You go read their work. You learn from them. The cycle continues. It’s not just about writing papers. It’s about being part of a living, breathing organism called the scientific community. We build on each other’s ideas. We test them. We prove some wrong. We evolve. There’s joy in that. There’s joy in knowing that your frustration today might lead to someone else’s breakthrough tomorrow. There’s joy in watching your idea, once scribbled in the corner of a notebook, become the basis of someone else's research question. And maybe, just maybe, someone will look at your name and think, This is the paper that helped me. That’s what makes research beautiful. That’s what makes it fun. And that’s the spirit behind BLUWR—a collective of curious minds, building science not for credit, but for the love of it. A place where ideas grow, where collaboration thrives, and where research feels like what it was always meant to be: deeply human.

Personality Psychology Part 1 : The Mind of a Control Freak 7537

Anas Bedraoui, 4 mon.
A control freak is someone who has an overwhelming need to dictate people and situations, often to the point of obsession. Their desire for control stems from different factors, including anxiety, insecurity, or even underlying psychological conditions like Obsessive-Compulsive Disorder (OCD). While they may believe their meticulous oversight ensures perfection, their behavior often damages relationships and creates unnecessary tension. Why Do Some People Become Control Freaks? Anxiety: A person who struggles with anxiety may attempt to control everything around them to minimize uncertainty and reduce stress. Insecurity: Those with low self-esteem or a history of being controlled themselves may develop controlling tendencies as a defense mechanism. OCD and Perfectionism: Some individuals have an intense preoccupation with perfection, organization, and structure, making them hyper-controlling in their interactions. ---- Signs of a Control Freak: They rarely, if ever, admit when they are wrong. They blame others for mistakes rather than accepting responsibility. Delegating tasks is difficult because they don’t trust others to do things correctly. They micromanage, obsessing over small details rather than focusing on the bigger picture. They may try to undermine others' reputations to maintain a sense of superiority. Lying—whether about their behavior or yours—is a common tactic for maintaining control. Extreme jealousy often accompanies their need for dominance. ---- The Desperation of Losing Control: The most dangerous moment is when a control freak feels they are losing their grip. When this happens, they will do everything in their power to regain control—no matter the cost. They may reach out to your surroundings, trying to manipulate your friends, family, or colleagues against you. They could spread false information, twist narratives, or play the victim to make you look like the problem. In extreme cases, they might resort to emotional or psychological attacks, using guilt, fear, or even threats to pull you back into their influence. ---- Not everyone responds to control the same way. If you attempt to dominate someone who recognizes what you're doing—and knows how you operate—they may see it as a threat rather than an inconvenience. Some people will leave you for good, cutting ties entirely rather than tolerating manipulation. Others will wait for the right moment to strike, using your need for control against you. They may anticipate your actions, exploit your weaknesses, or retaliate in ways you never saw coming. A control freak often believes they are in charge, but in reality, those who understand manipulation can either escape it or turn it into a weapon. ---- If you are experiencing this, just be pure, open you heart, and pity them, don’t hate them. Beneath the manipulation and obsession is a person who is suffering—someone so afraid of uncertainty, failure, or rejection that they feel the need to control everything around them. They may hurt others, but in the end, they are hurting themselves the most.

What I Learned in 2024 During My PhD (Beyond Academia) 7761

Anas Bedraoui, 6 mon.
When people ask what I’ve learned during my PhD, they usually think it’s all about science—reading papers, running experiments, gathering data. But honestly? That’s barely 20% of what I’ve learned this past year. The real lessons have nothing to do with lab work. It’s more about how you plan. I’ve learned to pause, think things through, and focus on long-term goals. Not everything needs a fast answer, and not every problem needs to be fixed right away. The best decisions come when I keep my emotions in check and focus on strategy. Waiting is tough. Progress can be painfully slow. But I’ve learned that good things take time. Getting frustrated doesn’t help—staying calm does. Spending hours working alone makes you figure out who you really are—what motivates you, what stresses you out, and how much you can handle before you reach your limit. Some tasks felt pointless—reading papers I wasn’t excited about or presenting when I wasn’t ready—but those things made me better. The things I dreaded the most taught me the most. I’ve also realized that communication is about more than speaking—it’s about making people understand. Breaking down complex ideas is just as important as knowing them. How you explain things shapes how people see your work. And thinking critically isn’t just for science—it helps you understand the world better, question things, and spot what others might miss. I stopped waiting to feel “ready.” Confidence doesn’t come from knowing everything—it comes from showing up, trusting what you’ve learned, and getting better each time. I’ve also started thinking of my future like a game of chess—every move counts. Emotional decisions don’t last, but careful ones do. I’ve learned you can’t force your way through everything. Sometimes, you need to know when to speak, when to listen, and when to take a step back. Being diplomatic doesn’t mean you’re weak—it means you’re smart enough to handle things without making everything a fight. These lessons weren’t in any textbook. They came from real moments—the tough ones, the quiet ones, and the ones that felt overwhelming. It’s more than learning skills—it’s understanding yourself and becoming stronger with every step forward. Still, you don’t have to figure everything out alone. When you seek advice from someone who knows you and genuinely wants you to grow, you can skip some of the slow, painful steps. They help you see blind spots and make your process faster and smoother.

One Year Writing on Bluwr 6500

Anas Bedraoui, 7 mon.
Bluwr. A space where writing feels free. No ads. No distractions. Just you and the words. When attention is currency, this feels like a quiet space. I don’t chase trends. I don’t worry about clicks. I write what matters to me. And somehow, it matters to others too. Every post is a chance to connect. A chance to learn. A chance to grow. Readers don’t just scroll past. They pause. They think. They reach out. Writing here feels real. Unfiltered. Authentic. No gimmicks. No pressure. Just pure expression. One year in, and the excitement hasn’t faded. Every time I hit publish, it feels like a small victory. A reminder that words have power. Bluwr gets it. It’s built for writers. Built for readers. Built for those who care about ideas. Bluwr doesn’t just stay in the present. It THINKS FORWARD. Supporting new ideas. Fueling creativity. Inspiring what’s next. Bluwr isn’t just a platform. It’s a mindset. A commitment to progress. A space where your ideas aren’t stuck in the now—They’re shaping the future.

Bluwr: My Experience with an SEO-Optimized Platform That Knows Me Better Than I Do 2960

Anas Bedraoui, 10 mon.
When I first started writing on Bluwr, I didn't think much about how well the platform was optimized for SEO. Like most writers, my primary focus was on crafting engaging content, sharing my thoughts, and hoping my articles would find their way to the right audience. But recently, I decided to conduct a funny little experiment that opened my eyes to just how effective Bluwr's SEO capabilities truly are. Curiosity struck me one evening as I was thinking about the digital footprint I’ve been leaving behind with my articles. With AI becoming increasingly sophisticated, I wondered just how much information was out there about me, pieced together from my work. So, I turned to GPT, and asked it a simple question: "What do you know about me?" The results were both fascinating and a little uncanny. GPT didn’t just know general facts; it provided a detailed account of my work, interests, and even some insights that I hadn’t explicitly mentioned in any one article but had implied across several. The source of all this information? My articles on Bluwr. This experience highlighted one major thing for me: Bluwr is incredibly well-optimized for SEO. Every article I had written, every topic I had explored, and every opinion I had shared was indexed and made easily accessible by search engines. Bluwr’s backend is clearly designed with SEO in mind. From the way articles are structured to how tags and keywords are used, everything seems to be geared towards making sure that each piece of content is easily discoverable. What struck me the most during my experiment was how Bluwr enabled GPT to aggregate and synthesize data about me. Individually, my articles were just that—individual pieces of content. But together, they created a comprehensive narrative that GPT could easily tap into. This got me thinking about the broader implications of writing on a platform like Bluwr. While my little experiment with GPT started as a bit of fun, it ended up being an insightful look into how powerful SEO can be when done right. Feel free to try a similar experiment yourself. You might be surprised at what you learn...

What’s All This Buzz About Monkeypox? 2449

Anas Bedraoui, 11 mon.
2 min read.
Everyone’s talking about it. Monkeypox. It’s all over the news, and people are scared. But what is it, really? Should we be worried, or is this just another overhyped health scare? Monkeypox isn’t something new. It was first identified in 1958 in monkeys, which is how it got its name, but the first human case was recorded in 1970 in the Democratic Republic of the Congo. For decades, it remained mostly confined to Central and West Africa, with only occasional cases elsewhere. But now, it’s spreading faster and wider than before. That’s why it’s making headlines and causing concern globally. Let’s be clear: monkeypox is not COVID-19. It spreads differently, and it’s generally less contagious. But it can still be serious, especially for certain groups like young children, pregnant women, and those with weakened immune systems. So, how does one catch monkeypox? Mainly through close contact with an infected person or animal. This could mean direct skin-to-skin contact, being exposed to respiratory droplets, or touching contaminated objects like bedding or clothing. Unlike COVID-19, which can spread through the air over distances, monkeypox requires more direct contact. The symptoms can be unsettling. It usually starts with flu-like symptoms — fever, headaches, muscle aches, and swollen lymph nodes. Then, within a few days, a distinctive rash develops, often beginning on the face and then spreading to other parts of the body. These rashes turn into raised bumps that eventually fill with fluid, becoming painful blisters. In some cases, these lesions can leave scars. Despite these symptoms, most people recover within two to four weeks without the need for serious medical intervention. But complications can occur, especially in those with underlying health conditions. Here’s the silver lining: there are vaccines. If you’ve been vaccinated against smallpox, you might already have some level of protection against monkeypox. This is because the viruses that cause smallpox and monkeypox are closely related. In fact, the smallpox vaccine has been shown to be about 85% effective in preventing monkeypox. For those without prior vaccination, newer vaccines specifically targeting monkeypox are now available. Now, let’s talk about the bigger picture. The resurgence of monkeypox outside of Africa raises questions about how well-prepared we are for emerging infectious diseases. With increased travel and global interconnectedness, diseases that were once localized can spread quickly across borders. This situation reminds us of the importance of strong public health systems and the need for global cooperation in disease surveillance and response. But let’s not panic. Monkeypox is serious, but it’s also manageable with the right precautions. For more detailed information, check out WHO’s page on monkeypox. So yes, monkeypox is something to be aware of, but with the right knowledge and precautions, there’s no need to panic. Stay safe, stay smart, and keep looking out for each other.
medium.com/@anasbedraoui

You Graduated and Don’t Know What to Focus On for a PhD Position? 2533

Anas Bedraoui, 11 mon.
2 min read.
I assume you’ve just earned your master’s degree. You might be feeling a bit lost. You’ve started applying for opportunities — Industry or Academia — but you’re still waiting for that interview opportunity. No one is answering your emails. I get it. You might be feeling frustrated, maybe even battling imposter syndrome. You’re thinking about enrolling in new courses to acquire enough skills to be ready for any opportunity, but you still feel very lost. Let me tell you exactly what I would do if I were in your place three years ago. Please read this article until the end. You will enjoy it, and I made it especially for you as a source of motivation, giving you exactly what you should focus on. Let’s assume first that you want to enroll in a good PhD program. Whenever I apply for an opportunity, I put myself in the interviewer’s shoes — in this case, your future supervisor. What does your future supervisor want from you? What’s your added value to their lab? Why should they recruit you? Your supervisor wants you to be the greatest version of yourself, wants to be proud of you, and wants your success to be their success as well. First, they want you to avoid distractions and focus on your PhD, producing great, interesting results, and discoveries that lead to high-quality publications. They want you to step out of your comfort zone, present at international conferences, bring added value to the lab, be a great representative, and never outshine them. Control your ego, be easygoing with the team — not a toxic presence — and remember, they don’t expect perfection, but they do expect you to do your best. I know you can be like that, but there are a few things you can do to make your application stand out. When writing emails to potential supervisors, have you read some of their most interesting, highly cited articles? Did you do some research beforehand and address specific points within your email? What did you accomplish during your master’s degree? Were you just an average student who passed exams, or did you do something exceptional that made you unique compared to most students? If yes, then mention it, talk about it, and sell it to your supervisor in your application. Show that you are unique. When writing an email, motivation letter, or research proposal, stop using templates or AI-generated content. Your supervisor is smarter than you think, and they will spot that because they’ve seen a ton of applications. They want originality; they want to know who you are and what you can do. Be original. You don’t have to make it perfect, just be yourself. I want you to create a unique application that will impress any professor who reads it. Make it stand out. Use your own creativity — you’ve graduated, which means your brain is still fresh, and you are smart. SHOW THEM THAT! Don’t apply for just one position — make different plans. You gotta be smart about it. Reach out to your previous professors, especially those whose work you found impressive, and gently ask them for a recommendation letter. Use your contacts, and take your time to make different plans, because this step is a big one toward your future goals. Be wise about it. This isn’t just about getting one position; it’s about setting up a foundation for your future. Different plans give you options, and options give you control over your path. Last but not least, if I were you, I would focus on reading a bunch of review papers in the field I’m interested in. Start doing the things your future supervisor would expect you to do in your first year: identify the scientific question that interests you, find your unique approach, and start working on answering it. It’s your mission to find the gap in your field and fill it. You can begin working on that right now, while also doing the things I mentioned above. I’m not going to dig into the details here because I’ve kept this article a bit general, but if you have any questions, feel free to ask them directly.

Is PhD for you or not? 2879

Anas Bedraoui, 11 mon.
Why is a PhD so tough? If I still get the chance to do a PhD, should I still consider doing it? I get plenty of questions asking me, “Why should I apply for a PhD? What are the benefits? Where, in what field, and with which supervisor should I consider doing it?” I will answer all these common questions in this article and give a few pieces of advice for graduate students and anyone hesitating to enroll in a PhD program. First things first, if you ask any PhD candidate or someone with a PhD about their experience, we all share the same answer: “PhD is tough.” But why? A PhD program is meant to shape you personally and professionally. It’s a minimum of three years where you discover your weaknesses, build a strong foundation of expertise, focus, and social dynamics, and it takes you out of your comfort zone. I’ll explain everything in detail with examples. The idea I had about a PhD when I recently graduated is completely different from what I am experiencing right now. Before, I thought a PhD program was all about publishing papers, and back then, for me, a paper could be done in less than four months. I mean, indeed, but that’s only for a mediocre paper with no impact, which could be published in a normal to predatory journal. Now I realize that publishing a high-quality article takes years of hard work, consistency, collaboration with a team of experts, making mistakes, conducting experiments, re-conducting experiments, taking critical advice from your supervisors, and implementing it effectively. Even then, you may or may not get the expected results. You may feel frustrated and get a bit depressed since you spent at least a year working on an approach that now seems no longer promising. That’s one side. The other side is psychology. What I mean by that is how you can feel really down, but regardless of your feelings, you discover your passion that can boost you and give you the purpose to balance your PhD and personal life. Then there is a critical aspect, which is your supervisor. You and your supervisor are two different people. Your supervisor has more experience than you, and as you’re conducting your PhD, doing the experiments, once you get critical feedback from your supervisor, you may take it personally and start thinking negatively about your experience, assuming he’s not helping you but just criticizing your work. That’s not true. What you actually learn about a PhD is that your supervisor’s success is yours as well, and vice versa. Since he has more experience than you in publishing high-quality articles, you should definitely forget about your ego, start communicating with him, and learn from him, because at the end of the day, you are still a student, and that’s what’s great about the PhD experience. Besides publishing, which is just a small part of your PhD program, you learn how to communicate your research area and results in a smooth way that anyone with a different background, or even a 5-year-old kid, could understand. You also learn how to sell your research, which means that you can definitely be a great candidate for the industry in the future, not just academia. Public speaking is another important skill you learn in a PhD since it is required to present your work at international conferences and congresses in front of highly valued speakers. You start to appreciate criticism and see it as a new way to improve yourself. If your primary goal is to improve yourself, be self-aware, and be better, then a PhD program is for you. If you are not, just forget about a PhD program because you will struggle, start comparing yourself with others, or may stop comparing yourself with others in a bad way that may lead you to become a narcissistic psychopath who thinks his PhD thesis is going to change the world and that everything he does is what matters, while what others do is completely irrelevant. At the end of the day, a PhD program is just a way to reach your higher goals, and if you see it as it’s supposed to be, then you’re going to have an enjoyable experience, full of learning, and enjoy science as it’s supposed to be. My Advice for Future PhD Candidates: - Your Supervisor: The first thing you should look for is your supervisor rather than the subject of your thesis. Your supervisor is the one you will be working with every single day for at least four years. He should be a good human being, skilled, and inspirational because their words can be a great motivation for you. Otherwise, if not, your experience is just going to get worse and worse, and you may quit. - Self-Improvement: Consider if you really want to improve your weaknesses and become a better version of yourself. Are you ready for high criticism of work that you spent years on? Would you accept that? If yes, then go for a PhD. - Academia: Academia is super toxic. Are you ready to engage in what might be a toxic environment and learn how to get the good side from it? If yes, then trust me, you will be perfectly shaped after your PhD, and you will be a great fit for both academia and industry. - Financial Goals: If your goal is to get money rather than improving yourself, just forget about academia because it will simply slow down that process of getting money as soon as possible. ---- To answer the first question, if I get the chance to start my PhD with the same conditions, the same supervisor, and the same thesis director, I would definitely follow the same path. Hell yeah, I love it!
medium.com/@anasbedraoui

Finding the Middle Ground 2854

Anas Bedraoui, 11 mon.
Comparing ourselves to others often leads to frustration and disappointment. Picture this: you're scrolling through social media, and you see an old friend from high school posing in front of their brand-new sports car, while you're still driving a car that predates the invention of the smartphone. You start to wonder where you went wrong. Did you choose the wrong career? Should you have invested in Bitcoin instead of student loans? These thoughts spiral until you're convinced that your only way out of this rut is to fake your own death and start a new life as a reclusive writer in a cabin somewhere deep in the woods. In reality, comparing yourself to others is like playing a game where the rules are rigged from the start. Everyone is on a different journey, with varying challenges, opportunities, and, let's be honest, different levels of Photoshop skills. We tend to compare our behind-the-scenes mess with someone else's highlight reel, forgetting that their life probably includes the same boring Tuesday afternoons and Netflix binges as ours. Yet, this habit of comparison can warp our sense of reality, making us feel perpetually "less than" others and chipping away at our self-esteem until we're left contemplating the logistics of that cabin in the woods. ---- But let's flip the script. What happens when we avoid comparison altogether? Imagine you decide that you're going to be your only measure of success. No one else matters. You wake up each morning, look in the mirror, and say, "I'm the best thing that's ever happened to humanity since sliced bread." At first, this mindset feels empowering. You walk around with the confidence of a motivational speaker who's just sold out a stadium. But soon, things take a turn. You start to dismiss others' achievements because, clearly, no one can hold a candle to your brilliance. You become that person who interrupts every conversation to talk about your latest accomplishment, even if the conversation is about someone's grandma's funeral. ---- This path leads to an inflated ego, where your sense of self-worth balloons like a cheap helium balloon at a child's birthday party—ready to burst at the slightest pinprick of criticism. Narcissism, at its core, is a personality trait characterized by an inflated sense of self-importance, a need for excessive admiration, and a lack of empathy for others. When we avoid any comparison, we risk sliding into this mindset, seeing ourselves as above others, and losing the ability to connect with those around us. This self-centered view can damage relationships, create isolation, and ultimately leave us empty, as we become more invested in maintaining an image than in nurturing genuine connections. Ego and narcissism aren’t just about an inflated self-image; they can also manifest as defensiveness and an inability to accept criticism. Imagine someone pointing out a flaw in your work. Instead of seeing it as an opportunity for growth, you might react like a celebrity whose latte order was just messed up—indignant and defensive. This behavior alienates others and stunts personal growth, as the ego becomes a barrier to learning and improvement. Balancing these extremes requires a conscious effort. Instead of using comparison as a yardstick to measure our worth, we can use it as a tool for motivation and inspiration. Picture yourself as a runner in a marathon. Instead of focusing on how far ahead the others are, you focus on your own pace, using the leading runners as guides to improve your speed. Along the way, you celebrate every milestone you reach, even if it's just passing the water station without tripping over your own feet. Practicing humility and staying open to feedback keeps that ego in check. Recognizing that everyone is a work in progress allows us to approach criticism not as a threat but as a chance to learn and grow. This mindset keeps you grounded and prevents that balloon from getting too full of hot air. Humility also fosters empathy, enabling us to connect with others more meaningfully, appreciating their successes without feeling threatened. Comparison is a natural part of being human, but it's essential to approach it with a sense of humor and perspective. Letting it dominate our thoughts leads to frustration, while avoiding it entirely risks fostering narcissism. Finding the middle ground allows for personal growth, rooted in a realistic understanding of ourselves, balanced with empathy and self-awareness. What do you think? Do you find yourself comparing your life to others, and if so, how does it affect you? How do you keep your ego in check while staying motivated to grow? What strategies do you use to find a healthy balance between self-reflection and self-confidence?

Snake Venom That Does Nothing to a Honey Badger, Kills a Human 3316

Anas Bedraoui, 12 mon.
The honey badger is one of nature's toughest creatures. Despite its small size, this fearless animal isn't afraid to take on some of the most dangerous predators, including venomous snakes. What’s truly fascinating is that the snake venom that can kill a human has little effect on a honey badger---- The honey badger, also called a ratel, lives in Africa, Southwest Asia, and parts of India. It’s known for its aggressive behavior, strong build, and thick, loose skin, which makes it hard for snake fangs to deliver a full dose of venom. This tough skin is one reason why honey badgers can survive snake bites that would be deadly to other animals. ---- But the honey badger's resistance to venom isn't just about its skin. Scientists have discovered that honey badgers have special adaptations at the molecular level. Snake venom typically attacks nerve cells by binding to specific receptors. However, the honey badger's receptors have evolved to be less affected by these toxins, allowing the badger to survive bites that would be fatal to humans. ---- Another interesting aspect is how honey badgers react when bitten. They might show signs of being affected by the venom, such as slowing down or swelling, but they often recover quickly. This suggests that their bodies have proteins or other molecules that neutralize the venom, helping them bounce back after an encounter with a deadly snake. FASCINATING, right?

Can You Become a Millionaire by Working on Venom? Yes! 2565

Anas Bedraoui, 12 mon.
1 min read.
The idea of becoming a millionaire might conjure images of tech startups, real estate investments, or Wall Street. But working with venom can be your ticket to wealth, thanks to its significant medical and commercial potential. ---- Venom, produced by creatures like snakes, spiders, and scorpions, is a complex mixture of proteins and peptides. These toxic cocktails hold incredible potential for medical applications, creating a profitable intersection of nature and science.---- Venom-derived drugs have made significant impacts in medicine. For instance: - Captopril, derived from the Brazilian pit viper's venom, generates over $1 billion annually in revenue. - Prialt, a painkiller from cone snail venom, can cost up to $20,000 per year per patient. ---- The pharmaceutical industry constantly seeks new compounds for effective treatments. Venom-derived substances are particularly appealing, leading to substantial investments in research and development. This can result in lucrative patents and partnerships.---- Venom production and farming are other profitable ventures. Companies like Amsaal Venom Farm LLC specialize in producing and distributing venom for research and antivenom production. High-quality venom can sell for up to $5,000 per gram, depending on the species and purity.---- Owning patents on venom-derived compounds is highly lucrative. Licensing these patents to pharmaceutical companies can yield substantial royalty payments. For example, licensing agreements typically offer 3–5% royalties on net sales. A successful drug generating $500 million annually could provide $15-$25 million in royalties.---- Imagine discovering a new venom-derived compound that becomes a best-selling drug. With an annual revenue of $1 billion and a 3% royalty, you could earn $30 million per year. Alternatively, running a venom farm producing 100 grams of high-quality venom per year could generate $500,000 annually, assuming a $5,000 per gram price.

How Nature's Deadliest Creatures Influence Medicines? 2407

Anas Bedraoui, 12 mon.
2 min read.
When we think about the most dangerous animals in the world, we often imagine deadly snakes, venomous spiders, or stinging scorpions. These creatures are feared for their powerful venoms, but what if I told you that their venoms could save lives? It may sound surprising, but many scientists are now using these dangerous venoms to create new medicines. Here are some of my thoughts on this fascinating topic. Spider venom might give you chills, but it is also giving hope to people who suffer from strokes. The Australian funnel-web spider (Atrax robustus) produces a venom that contains a peptide called Hi1a. This peptide has been found to protect brain cells from damage caused by a stroke. Researchers are studying Hi1a to create treatments that could save the lives of stroke victims and help them recover more quickly. Snakes are some of the most feared animals on the planet, but their venom is helping to treat serious illnesses. For example, the Brazilian pit viper (Bothrops jararaca) produces a venom that contains a molecule called bradykinin-potentiating peptide (BPP). This molecule has been used to develop a class of drugs known as ACE inhibitors, which are commonly prescribed to treat high blood pressure and heart failure. These drugs work by relaxing blood vessels and reducing blood pressure, turning a deadly venom into a lifesaving medication. Scorpion venom is another powerful substance that is being turned into medicine. Researchers have found that a protein in scorpion venom, chlorotoxin, can bind specifically to cancer cells without affecting healthy cells. This discovery has led to the development of a drug called Tumor Paint, which helps surgeons see cancer cells more clearly during surgery. The venom of the deathstalker scorpion (Leiurus quinquestriatus) is being harnessed to ensure that cancerous tissue is removed more precisely, reducing the risk of recurrence. The ocean is home to many venomous creatures, like cone snails and jellyfish. The venom of the cone snail (Conus magus) contains a compound called ziconotide, which has been developed into a drug for severe chronic pain. Ziconotide works by blocking calcium channels in nerve cells, preventing pain signals from reaching the brain. This non-opioid painkiller offers a powerful alternative to traditional pain medications and has been a significant breakthrough in pain management. Bees and wasps are often seen as pests, but their venoms are being used to help treat autoimmune diseases. Melittin, a peptide found in bee venom, has shown potential in treating conditions like multiple sclerosis and rheumatoid arthritis. Melittin can modulate the immune response and reduce inflammation. Scientists are working to isolate and modify melittin to enhance its therapeutic effects while minimizing side effects, offering new hope to patients with these challenging conditions. The Gila monster is a venomous lizard whose saliva contains a hormone called exendin-4. This hormone has been turned into a drug called exenatide, which helps people with type 2 diabetes manage their blood sugar levels. Exenatide mimics the action of a natural hormone that stimulates insulin release and inhibits glucagon production, effectively controlling blood glucose levels. It's amazing to think that a substance from a lizard's mouth can help millions of people control their diabetes. Centipedes might seem like creepy crawlies, but their venom is showing promise as a pain reliever. The venom of the Chinese red-headed centipede (Scolopendra subspinipes mutilans) contains a peptide called SsTx. SsTx can block pain signals by inhibiting sodium channels in nerve cells, offering a new approach to pain management. Researchers are synthesizing SsTx in the lab and conducting trials to evaluate its effectiveness and safety, potentially leading to new, non-addictive painkillers. It is truly fascinating how scientists can transform deadly venoms into life-saving medicines. Studying these natural toxins, researchers are finding new ways to treat some of the most challenging diseases and conditions. This innovation shows the incredible diversity of nature and emphasizes the importance of preserving these species and their habitats. The transformation from venom to cure is a remarkable testament to human ingenuity and the power of nature. Attached, please find our open-source scientific article explaining everything in detail.
sciencedirect.com/science/articl...

Artificial Illusion: The Hype of AI - Part 1 3097

Anas Bedraoui, 1 y.
I personally see AI as a hype that will slow down with time. Nowadays, people include AI in their projects to seize opportunities. For example, if you have a failing business, just add the word AI and you might attract investments. If you're doing research, switch to AI or include a part of it, even if it's not necessary, and you may receive funding. AI is becoming a buzzword, and if you believe it's not, you might get frustrated. You might feel unworthy as a human and worry about being replaced by a robot that lacks emotions, creativity, and the incomparable qualities of the legendary creation: humans. As I mentioned in a previous opinion article, "Just use AI in your speech and you'll sound fancy." This trend has permeated many sectors. I’ve had conversations with CEOs of startups that claim to use AI for groundbreaking innovations :). When I asked them simple questions about the models they used, the reasoning behind their choices, and the specific applications, they would talk broadly about AI—just AI, yes AI, and that’s it. It's reminiscent of the old saying, "Fake it till you make it," but with a modern twist: "Artificial Illusion." As Mark Twain once said, "It's easier to fool people than to convince them that they have been fooled." This seems particularly true in the world of AI hype. The enthusiasm for AI has led to a phenomenon where merely mentioning it can lend credibility and attract resources, even when the actual implementation is minimal or superficial. This trend not only dilutes the genuine potential of AI but also risks disillusioning stakeholders who may eventually see through the facade. True innovation requires substance, not just buzzwords. If Shakespeare were alive today, he might quip, "To AI, or not to AI, that is the question." The answer, of course, is that while AI has its place, it’s not the end-all and be-all. We should remember Albert Einstein's wise words: "Imagination is more important than knowledge." AI lacks the imagination and creativity that humans bring to the table. The real secret to success isn’t in the latest tech jargon, but in honest, hard work and genuine innovation. So next time someone dazzles you with their AI-powered business model, just remember: A little skepticism can go a long way. Or as George Bernard Shaw put it, "Beware of false knowledge; it is more dangerous than ignorance."

I Spent 7 Days in Singapore... My Life Changed, Here is Why 2720

Anas Bedraoui, 1 y.
Spending a week in Singapore was an unforgettable experience that left a lasting impact on my life. From the moment I arrived, I was captivated by the city's unique blend of modernity and tradition, its vibrant culture, and its cutting-edge innovation. Here are the key moments and discoveries that made my stay transformative. Day 1: A Fusion of Cultures Singapore is a blend of various cultures, and this was immediately evident. Wandering through neighborhoods like Chinatown, Little India, and Kampong Glam, I immersed myself in diverse traditions, cuisines, and architectures. Each area told a story of the people who have made Singapore their home. In Chinatown, I visited temples and savored street food while chatting with local shopkeepers (mainly in Chinese Mandarin) who shared the history of their businesses. Little India dazzled me with its colorful markets and the aroma of spices, where I learned about Indian festivals and rituals from friendly vendors. Kampong Glam, with its vibrant street art and the majestic Sultan Mosque, offered insights into Malay culture. This cultural immersion made me feel connected to the global community, appreciating the rich traditions that coexist harmoniously in Singapore. Day 2: A Green Oasis in a Concrete Jungle The Gardens by the Bay was a highlight of my trip. The futuristic Supertree Grove and the serene Cloud Forest left me in awe of how Singapore harmonizes nature with urban life. I spent hours exploring the lush landscapes, marveling at the diversity of plant species. A gardener I met shared stories about the meticulous care and effort that goes into maintaining these green spaces, emphasizing Singapore's commitment to sustainability and green living. This encounter inspired me to think more about how I can incorporate eco-friendly practices into my daily routine. Despite the city's strict rules, which made finding a smoking area a bit of a challenge, I appreciated the clean and green environment that these regulations help maintain. Day 3: Innovation and Inspiration Attending the 22nd World Congress of the International Society on Toxinology was the primary reason for my visit. Here, I had the honor of presenting my research and engaging with some of the brightest minds in the field. Conversations with researchers like Pr. Jan Tytgat and Pr. Manjunatha Kini opened my eyes to new possibilities in my work. Their innovative approaches and groundbreaking discoveries reignited my passion for scientific research. The congress was held at the National University of Singapore (NUS), and I was struck by the beauty and modernity of the campus. NUS, with its state-of-the-art facilities and vibrant academic atmosphere, stands as a testament to Singapore's commitment to education and research excellence. Day 4: Culinary Adventures and Unexpected Encounters Singapore's food scene is legendary, and I made it a mission to try as many local dishes as possible. From hawker centers to high-end restaurants, each meal was a culinary adventure. Trying dishes like Hainanese chicken rice, laksa, and chili crab expanded my palate and appreciation for the artistry of food. At a late-night food stall in Newton Food Centre, I struck up a conversation with a group of construction workers who shared their experiences and struggles. Their stories of hard work and resilience left a lasting impression on me, highlighting the human side of Singapore's rapid development. Despite the strict laws, the city felt incredibly welcoming and orderly, contributing to its reputation as a clean and safe destination. Day 5: A Glimpse into the Future and a Brush with Reality A visit to the Singapore Science Centre and Fusionopolis showcased the country's commitment to technological advancement. The innovations in AI, biotechnology, and sustainable development were impressive and motivating. Seeing these advancements firsthand made me more enthusiastic about the potential of my own research in AI for drug discovery. Later that night, while exploring Geylang, a less-touristy part of town, I had an unexpected encounter with a group of youths who shared tales of their tough upbringing and the challenges they face. This stark contrast to the city's polished exterior added a layer of depth to my understanding of Singapore, showing that even in a seemingly perfect city, there are stories of struggle and resilience. Day 6: Reflection and Growth On my penultimate day, I took some time for personal reflection at the serene East Coast Park. The peaceful environment provided the perfect backdrop to contemplate my experiences and the new insights I had gained. A local fisherman I met there shared his life philosophy, emphasizing the importance of balance and mindfulness. This interaction made me realize the importance of balancing professional aspirations with personal well-being. The warm, tropical weather, although humid, added to the overall tranquility of the park. As I sat by the sea, watching the ships go by, I felt a profound sense of calm and clarity, understanding the need to find harmony in life. Day 7: Farewell with a New Perspective As my time in Singapore came to an end, I felt a profound sense of gratitude. The city's spirit of innovation, cultural richness, and commitment to sustainability had left an indelible mark on me. I was especially struck by the friendliness and honesty of the people. Everywhere I went, locals were ready to help, whether it was giving directions or sharing their stories. Unlike many other cities, I didn't encounter any scammers or beggars, which added to the sense of safety and trust. I returned home with a renewed sense of purpose, inspired to incorporate the lessons I learned into my everyday life and research. My seven days in Singapore were more than just a trip; they were a series of experiences that changed me. This dynamic city showed me the power of diversity, the importance of innovation, and the value of sustainability. My interactions with people from all walks of life, from researchers to laborers to those on the fringes of society, gave me a more nuanced perspective. My life was changed in ways I never expected, and I am eager to see how these experiences will shape my future.
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