Think Forward.

Science

Only education can counteract incivility and aggression in society... 562

A Caïd copiously wedged in public by a young girl in Témara. Another had his head smashed in and his arm broken in the peaceful Oasis of Aoufous. A third was generously slapped in Mohammadia. A policeman stabbed in the neck by a young man who had come to lend a helping hand to his mother, a shopkeeper occupying the public space. A teacher savagely attacked with a knife by a pupil in Erfoud. A colossus causing chaos in the beautiful Rabat city railway station. A road accident not far from Merzouga, where a speeding driver hit a peaceful American tourist who had come to enjoy the wonders of the Kingdom; both died instantly. That's too many violent incidents for one week. Far from conducting a psychological or psychiatric analysis of these cases, we can nonetheless find similarities and a few points in common, namely: incivility, overexcitement, violence and obvious distress, provoking strong emotion at the scene and commotion among those confronted with these news items in the media. One wonders whether we are not confusing people suffering from proven mental disorders with ordinary citizens who, at some point, may disrupt public order or commit unforgivable or even irreparable acts. This is not a misguided shortcut, far from it. Back in 2022, the HCP told us that 48.9% of citizens suffered from mental disorders. Who is going to rush at a policeman with a knife in his hand or drive without measuring the danger, if not someone who is abnormal? Who doesn't respect the life of others if not someone monstrous? Would the woman who rushed at the civil servant have done so if she were psychologically stable? Any dangerous behavior, any action that disrupts public peace and quiet is indicative of latent evil. At times of great distress, it will manifest itself in excess and aggression. Distress and psychological instability are often interconnected, indicating deep-seated anxiety, a probable lack of affection and self-esteem, and hidden suffering in the family, at school, at work and in society. Harassment, fatigue, alcohol and drugs are never far away. This leads to, and legitimizes in the eyes of the individual, acts that he or she may, however, regret in the moments that follow. Negative impulses appear at times of stress and are common when we are sleep-deprived. Everyone knows that aggression is more than present in our daily lives during Ramadan. Insulting, slapping, speeding and stabbing all have a common denominator. The loss of self-control reveals a deep-seated psychological instability. Various situations will bring this weakness to the fore when, for example, we feel that our dignity has been damaged, our honor impugned, our honorability scorned by the actions and behavior of others. So, we act, and unfortunately, we act badly. It has to be said that when it's not a question of real illness but rather of acquired or suffered behavior, then the lack of instruction, of education, will have played a fundamental role in the formation of deviance. A lack of education in the family, at school and in society is the lever that generates a lack of respect, tolerance and self-control. Education remains the only vector for socialization. The family and then the school are the first structures of socialization. It is here that future citizens learn the rules of community life, respect for the integrity of others' bodies, politeness and respect for others. This is where peaceful interaction in society is shaped. Clearly, the failure of families to play their vital role, the absence of clear points of reference and positive role models, the proliferation of repetitive nihilistic discourse and destructive propaganda promising a better world elsewhere, all encourage disrespectful, aggressive and violent behavior. Don't Moroccans feel unhappy? Families, schools, clubs and associations of all kinds must develop young people's benevolence, solidarity and empathy, enabling them to better understand the emotions of others and avoid brutality. Activity, particularly physical education from primary school onwards, has a lasting impact on emotional education and conflict management, through obedience to pre-established common rules that are respected by all. Playing sport helps children learn to manage their emotions, thereby reducing petulance. Young people learn to express their frustrations in ways other than violence. This helps to drastically reduce tensions. Mediation by referees enables conflicts to be resolved and respectful behavior to be integrated from an early age, resulting in calmer relations in the community. Adults and institutions must play their role as role models, teachers first and foremost. Their qualifications must not be approximate, either in technical terms or in their ability to pass on values. If aggression and violence are on the increase, it's because adults, parents, teachers and authority figures have failed. Are they aware of this? Those in power must understand that there is no alternative to education, and to achieve this, school codes, fashions and curricula must be revisited and geared towards socialization values. Teachers must be properly trained and no longer recruited on the job. Tinkering with physical education at primary school needs to stop. This subject is extremely important from a very young age. It needs to be strengthened later, in colleges and lycées, with more hours taught by qualified, volunteer teachers. Finally, sport must have a proper place in universities. It's a shame that this won't be the case in 2025. The world of sport must play its part and assume its responsibilities. It's hard to believe that the number of members of sports clubs and associations is still very low, at just over three hundred thousand. For some time now, it has been thought that religious education alone was capable of fulfilling the mission of teaching values. This has not worked, and we need to recognize this without demagoguery and with courage. Our prisons are overcrowded with young people who would have no business being there if the system really worked. Favoring punishment alone to deal with incivility and aggressive behavior is not efficient. Only by taking an educational approach can we better understand the underlying causes and take lasting action on any damaging phenomena. This is the only way to bring about change and bring about lasting social harmony and prosperity.

The Real Reason Scientists Keep Going 644

They say the hardest thing to do is research. I mean science, right? But you have no idea how fun it actually is. When you're surrounded by a team of geniuses, each one bringing a different skill to the table, something magical happens. It's not a competition. It’s a quiet orchestra of minds. Everyone has their own zone of brilliance, and yet, everyone stays humble. Why? Because we all know that knowledge is never complete. You know things I don’t. I know things you don’t. And that’s perfectly fine. That’s how we grow. The beauty of research isn’t in instant success. It’s in the struggle. It’s in those long days and nights spent reading papers, writing code, running experiments, and getting nowhere. And then suddenly, a small insight hits you like lightning. A pattern. A correlation. A concept that no one else has connected before. That moment when something clicks—that’s the moment you realize why you do this. But let’s zoom out. In the grand scheme of things, your work is just one drop in an ocean of scientific progress. And still, that drop matters. You publish. Someone reads your paper, maybe in another continent. They find value in it. They cite it. You see the citation. You go read their work. You learn from them. The cycle continues. It’s not just about writing papers. It’s about being part of a living, breathing organism called the scientific community. We build on each other’s ideas. We test them. We prove some wrong. We evolve. There’s joy in that. There’s joy in knowing that your frustration today might lead to someone else’s breakthrough tomorrow. There’s joy in watching your idea, once scribbled in the corner of a notebook, become the basis of someone else's research question. And maybe, just maybe, someone will look at your name and think, This is the paper that helped me. That’s what makes research beautiful. That’s what makes it fun. And that’s the spirit behind BLUWR—a collective of curious minds, building science not for credit, but for the love of it. A place where ideas grow, where collaboration thrives, and where research feels like what it was always meant to be: deeply human.

Morocco's immeasurable archaeological wealth and the rewriting of history... 1280

Morocco has just decided to equip itself with a new archaeological museum, and it's thinking big. It will be the largest of its kind in Africa, covering an area of 25,000m2. It's both enormous and flattering. Some people will talk of excess, or simply fail to see the point. To this we must quickly retort: think again. If Morocco has always been considered to be of great archaeological interest, this interest has never been greater, except since the latest finds: the oldest homo sapiens fossil at Jbel Ighoud, not far from Safi; the oldest surgical procedures and treatments at Tafoghalt, near Berkane; the Bronze Age remains recently discovered near Wad Laou, on the prehistoric site known as KachKouch, not far from Tétouan; and the necropolis south of Tagounite near Zagora; those of the ornaments dated between 142 and 150 thousand years ago, uncovered in the Bizmoune cave near Essaouira; those of the 12-hectare farm near Oued Beht, a size never before known in North Africa, dating from the end of the Neolithic period, bearing witness to great wealth and highly evolved know-how. The list is extremely long. The clumsy notion that archaeological research and excavations are a luxury or the preserve of a few experts for their own pleasure is absolutely wrong. The importance of archaeological research to the writing of history is not debatable. It is fundamental. The remains and traces of the past help to complete, correct or confirm historical accounts. Fossils, structures and artefacts discovered on archaeological sites are all tangible evidence, providing an objective and nuanced view of vanished civilisations, particularly when they have left no written trace. Archaeology provides information about ways of life, culture, beliefs and human interaction, as well as the techniques used and the degree of evolution of vanished civilisations. It is essential for preserving and appropriating the national heritage, and hence that of humanity. It provides a milestone in human evolution and helps to explain what we are today. As the transmission of knowledge is crucial, archaeological research provides us and future generations with indisputable evidence of pride and identity. It is therefore essential for writing and rewriting history, which it cleans of the biases that some historians may have inserted here and there through ignorance or lack of evidence, and those that ideologists, for more or less laudable reasons, may have deliberately introduced as misleading orientations or aspects. The findings in Morocco call into question what successive generations have learned about their history and origins. Although it has been proven that the role of local populations in exchanges and in the construction of Mediterranean civilisation was extremely important, unfortunately we continue to peddle a biased history that ignores these contributions and archaeological evidence, which have now been proven beyond doubt. Since 1985, Morocco has had a National Institute of Archaeological and Heritage Sciences (INSAP). And it's not for nothing or by chance that archaeological research here is closely linked to heritage. Heritage means tangible evidence in the case of tangible heritage, and transmissible evidence in the case of intangible heritage. As it happens, Morocco is immensely rich in both. The researchers at INSAP are not going to contradict what has been said here, nor Ibn Khaldun, whom we venerate without respecting his doctrine. Today, it is essential to revisit the narrative that links the origins of Moroccan populations to any migration from elsewhere, and even less so from the east of the country; just as it is time to emphasise the evolution of these populations and their undeniable contributions to Mediterranean civilisation and therefore to the world. The people of this region have not been subjected to the civilisations of the region, they have made a great and important contribution, and this must be taught in our schools. Ignoring this truth creates deficiencies, particularly in the perception of identity. Nations need a historical frame of reference if they are to flourish. Some build it up out of nothing, whereas in Morocco it is there and self-evident. These truths could not be clearer. They must form the basis of our identity. The problems from which a certain fringe of the population suffers, particularly young people in search of an identity, and who unfortunately today are caught up in imported ideologies that can embrace dangerous extremism, can only be solved by rewriting history objectively, based on facts and historical evidence, from the most distant to the closest. Young people, particularly during adolescence and early adulthood, ask themselves profound questions about who they are, what they want to become and what place they occupy in the world. These questions are influenced by many factors, including of course family, culture, friends, personal experience and social environment, but they are also inevitably influenced by the history of the country in question. The further back in time this history goes, the more it is a source of pride and serenity. In this constantly changing world, where social networks and pressures of all kinds play a significant role, this quest for identity can be complex and sometimes a source of anxiety. Dismay can lead people to seek comfort elsewhere. Some may go so far as to think they are stepping back into an imaginary time and constructing a fictional world for themselves, watered down by ideologues serving obviously implausible causes. The investment in such a major archaeological museum has therefore come at just the right time to fill an extremely serious cultural gap, bringing together in a welcoming venue of respectable size a wealth of evidence of Morocco's rich history. Historians, for their part, should take up the question of identity in order to make up for the shortcomings and eliminate the biases. However, it is imperative that institutions take up the issue vigorously. First and foremost, the Ministry of Education must take the measure of the importance of revising the curricula and content of the history courses taught in our schools, without forgetting to train a significant number of specialists to improve research in such a cardinal field.

Couscous or the history of Morocco in a different way... 1860

The text below is not mine. It's a press release issued by researcher Nabil Mouline. For those who don't already know him, Si Nabil has a doctorate in history from the Université Paris-Sorbonne and Sciences Po Paris, which makes him both a historian and a political scientist. He is currently a researcher at the CNRS in Paris and the author of numerous articles and books, making him one of the leading specialists in the history of Morocco. He tells this unique, varied and rich history in his own way, with a narrative stripped of the frills and imprecision that can be found elsewhere. Nabil Mouline has made it his mission to bring Moroccans closer to their history and to make it easier for everyone to understand the characters, facts, situations and historical contexts, so as to help us, especially the younger generations, to grasp it, be inspired by it and make it our own; to live it to the full and be proud of it. In an exceptional recent educational effort, Si Mouline has teamed up with one of Morocco's best-loved faces, Mustapha ElFakkak, known as Swinga, to tell us this story in the form of an animated series. Si Mustapha's majestic and perfectly adapted voice gives the series a special appeal. It didn't take long for it to become a hit, as Moroccans are so thirsty to have their history told in a way other than what is imposed on them at school. The series is called Basmat Al-Tourath. The first issue is devoted to the history of couscous, while the second looks at the origins of the Almohad dynasty and the treasures hidden in Tinmel. Both have now amassed almost 400,000 views on YouTube. Below is the link to the first episode. Here is the text by Si Nabil Mouline. ‘Basmat al-Tourath: History as an issue of narrative sovereignty History is never neutral. It is a disputed territory, a battlefield on which the way in which people perceive themselves and the way in which they want to be perceived is decided. Far from being a simple archive of the past, heritage is a political and identity issue that determines the future. It is with this acute awareness that historian and CNRS researcher Nabil Mouline has conceived Basmat al-Tourath (The imprint of heritage), the very first animated series devoted to Morocco's tangible and intangible heritage. It's a project that doesn't just tell the story: it embodies it, reclaims it and brings it into the present. The stakes are twofold. On the one hand, it is about making history a living narrative, accessible to all, far removed from closed academic circles and fixed textbooks. On the other hand, it is a question of conquering ‘narrative sovereignty’, a fundamental concept which underlines the extent to which the way in which a people tells its past conditions the way in which it projects itself into the future. Basmat al-Tourath is therefore not simply a popularisation exercise, but an act of historical reconstruction, a strategic tool in the face of the contemporary challenges of cultural appropriation and memory battles. To give this project its full scope, Pr. Mouline has teamed up with Mustapha El Fekkak, alias ‘Swinga’, one of the most important popularisers in the Moroccan digital world. Together, they have decided to offer a format that combines scientific rigour and powerful storytelling, so that each episode is a truly immersive experience. A weekly programme during Ramadan Every Friday evening during the month of Ramadan, a new episode will explore a fundamental aspect of Moroccan heritage. The first episode, devoted to Tinmel, revealed to the general public the essential role played by this village in the High Atlas in the formation of the Almohad Empire, a veritable medieval superpower that ruled over a vast part of the Islamic world. This immersive approach has helped to anchor Tinmel in the collective imagination not simply as an archaeological site, but as a religious, intellectual and military centre that changed the history of the region. The next three episodes will tackle equally fascinating subjects, but their themes are deliberately being kept secret in order to maintain the suspense and impatience of the audience. The aim of this strategy is to transform Basmat al-Tourath into a truly unmissable cultural event, a time for discovery and reflection shared by Moroccans everywhere. History as a power issue Basmat al-Tourath has attracted so much attention because it responds to a pressing need: to give Moroccans back control over their own history, in the face of recurring attempts at cultural appropriation. The quarrels over the origins of the caftan, couscous or certain traditions are not simply folkloric disputes, but reflect deeper clashes over legitimacy and regional hegemony. Behind these debates, what is at stake is the crystallisation of ipsity, that awareness of oneself as a unique and distinct entity. Basmat al-Tourath not only recounts the past, she also highlights it as a precious heritage, an essential element of collective identity to be preserved and passed on. Morocco, with its remarkable historical continuity, has a responsibility to make its heritage known and recognised, ensuring that it is faithfully represented and fully appreciated. A project for transmission and outreach As well as showcasing our heritage, this series is also intended to be a tool for passing on our heritage. History that is not shared risks being erased over time. Basmat al-Tourath aims to anchor the Moroccan memory in new generations, offering them modern, accessible formats to help them better understand and appropriate their cultural heritage. By highlighting the richness and diversity of Morocco's heritage, this project also contributes to its influence beyond its borders. Heritage is an essential vector of cultural influence, and by promoting its historical and civilisational identity, Morocco is strengthening both its national cohesion and its attractiveness on the international stage. Basmat al-Tourath is much more than a simple series; it's a way of transmitting and raising awareness, a commitment to a living, shared history. It invites us to consider the past not as a fixed memory, but as a source of inspiration for building the future.
youtu.be/gqAur5NCQxk?si=K5E38l2U...

Rare diseases are not as rare as they seem... 3597

On Saturday february 22, I had the privilege of attending the 6th Rare Disease Day. Dr Khadija Moussayer, President of the Moroccan Rare Diseases Alliance, did me the honour, and I thank her for allowing me to sit at the table with the great medical professors who were going to discuss cutting-edge medical issues, requiring expertise and mastery of various subjects, as well as a deep humanism and a certain love of the country and its people. Unfortunately, I was only able to attend half of the proceedings, for which I am very sorry. So-called rare diseases are not in fact all that rare. They may be rare in terms of numbers, but they are so common that they are a daily occurrence in medical circles. They are rare because they are often invisible in a social environment that does not yet understand them or does not understand them well enough. They have a heavy impact on the emotional, sociological and economic life of families and enormously on the lives of the people affected. They are not yet adequately treated in university curricula, and are poorly understood by general practitioners and even by many paediatricians. Increasingly easy access to medical treatment is bringing these conditions out into the open, revealing their complexity and diversity to the medical community itself, as well as to families and society at large. They have an enormous psychological impact on families, disorientating them, tearing them apart and impoverishing them. Because of their genetic nature, they leave the families and individuals concerned in doubt, and plunge them into anxiety, disgust and self-hatred. Negative emotional reasoning and feelings of responsibility are never far away. This is often the driving force behind heavy social prejudice. Tradition and lack of education do the rest. They can go so far as to break up a family and often make the woman responsible. I myself met a young woman who was repudiated and rejected simply because she had given birth to a Marfan child. Her husband and family blamed her for the problematic birth and put her out on the street. Today, she is bringing up her child alone and is fighting to feed him, look after him, educate him and have his difference understood and accepted at school. Rare diseases are even more problematic, when you consider that doctors don't come across them every day in their consultations, and can even go so far as to ignore their existence. Their diagnoses are so complex at times that they require the intervention of multiple highly qualified specialities to define their existence and the protocols to be followed. More than in any other situation, the person diagnosed needs to be followed by more than one specialist at the same time. Is this always the case? Special tribute must be paid here to Professors Asmaa Quessar and Amine Benmoussa, who addressed the issue from the haematological point of view, explaining the complexity of the manifestations of some of these diseases and the impact of certain treatments. Professor FZ El Fatoiki focused in particular on skin manifestations, which in fact hide many things inside and are therefore crucial to diagnosis. Professor Imane Chahid received a special mention for her presentation on type 1 neurofibromatosis, which goes beyond café au lait spots. She recommended the creation of working groups involving all the specialities concerned, in order to limit patients' medical wandering and save time, efficiency and money. We need to explain to mothers that café au lait spots on a baby's skin are not ‘touhimates’. This ignorance can delay the treatment of a child with the disease, with all the consequences that can entail. That's true. One of the problems faced by families is medical wandering. Patients can spend a long time consulting and treating symptoms - ophthalmological, gastric, dermatological, etc. - before being diagnosed with a rare disease. Wandering is extremely costly. The testimony of a father who lost two children was particularly poignant. It was an emotional moment. The dignity and courage he showed make him an admirable character. I was reassured by the youth and commitment of more than one of the speakers. The sheer number and quality of people in attendance, and the questions asked by professionals and parents, show that there is a growing interest and expertise. The clarifications and commitment expressed on behalf of Moroccan geneticists by Prof. Karim Ouldim augur better days ahead, and a probably innovative approach to rapid and early diagnosis, and hence to treatment. In a way, he was responding to Prof. Chahid's call to work in clusters. Taking an interest in genetics brings us back to the question of data and the power of our computers. When it comes to genetics, AI is going to play a vital role, and if Morocco is not to suffer from the biases of others, it must compile and process its own data and train machines capable of understanding the specific genetic characteristics of Moroccans, because there are some, and that's normal. Any delay in this area will result in a lack of control, a squandering of skills, waste and a failure to respond effectively to the real needs of citizens. A fundamental question hovered over the room just before the lunch break: why is it that the work carried out by eminent Moroccans, the results of research carried out in the country and other discoveries are not taken into account in the establishment of public health policies? The gap between Moroccan research and the spheres of political decision-making is simply abnormal. A country can only progress from within through scientific research and hard work. Public policy must be based on innovation and research in the Moroccan field. Benchmarking is good, but research at national level is even better. I had the impression, and I was not the only one, that politicians go so far as to ignore, not to say despise, national skills, preferring to put their trust in foreign consultancies that are often ill-advised and ignorant of Moroccan realities and particularities. This is one of the reasons why our health and other systems are being hampered and impacted. It's unfortunate to be asking such questions in 2025. The day was an immeasurable success and deserves a great deal of media coverage, because the aim was to raise awareness. Lalla Khadija Moussayer and her team succeeded. We can never thank them enough for that. Thank you also for giving me the opportunity to meet Professor Mohammed Itri, an eminent paediatrician who left Rabat to teach at the CHU Ibn Rochd, but who never forgot his neighbourhood and his childhood neighbours...

The Historic NIH Decision that will change the Landscape of Research 4102

The NIH is the single major granting institution for research in the world and it has decided to cap the administrative overhead to 15%. This decision might forever change the organisation of major universities. To understand how university funding works in the US, when a researcher gets a grant, a significant part of that money (think 50% to 100%) usually goes to the administration of the university and not directly to research. For example if the administrative overhead is 60% on a grant of 1M$, either the research gets 40% (400k$) of the money and the university administration 60% (600k$), or the organism has to pay 1.6M dollars. This is what the NIH has been doing so far, creating a huge competition of for NIH grants. The NIH was the only organism that gladly paid the administrative overhead, while other institutions would cap it or completely refuse to pay it. Now the NIH will no be so accommodating. The huge administrative overhead is explained by the fact that over the year, administrative personnel in major universities has grown to far outnumber faculty, researchers and clinicians. Administrations at universities tend to follow extremely rigid and complex processes for almost anything. Most decisions and actions are regulated through a slow, rigid and scrutinizing process, either through a deep chain of command or through commissions that are slow to gather and have to debate every decision. This has been ongoing for a while at major universities because of virtually no negative feedback loop. The university could always raise the administrative overhead to pay for any new administrative processes it decides to implement. Major universities also do other things than research, and teaching. They are gigantic institutions with gigantic ramifications. Now more than ever, universities cannot afford to lower the standards on research. Because if they do, their faculty will not be less eligible for grants, and they might even loose the 15% that the NIH has promised to pay. The most likely outcome is swift lay offs of administrative personnel and the termination of many programs that are not conducive to outstanding research. Then, they will start doing more fundraising towards private donors, some of which already refuse to pay administrative overheads, requiring their money to go directly towards research. Institutions will also get closer to the industry, and will try to promote more startups, and spin-offs. But that will require major changes in administrative processes, money allocation and a lot more flexibility on intellectual propriety.
x.com/NIH/status/188800475939695...

AI is a Big Geopolitical Issue 4247

500 Billion dollars to keep the USA the number one power in AI followed by Deepseek whose creators claim has been trained on lower grade hardware, and now the AI summit in Paris. Modern AI is a breakthrough perhaps of the same magnitude as the steam machine or electricity, perhaps even bigger. It touches everything and, most importantly, for the first time it allows for the mechanization of intellectual work. Previous industrial major breakthroughs were focused on automatizing physical labor, AI offers the potential of automatizing the mind. The implications are hard to comprehend, but what is sure is that no nation wants to be left behind. The world of AI is segmented on a few pillars: 1 - The theory and software: mostly public and open-source 2 - The talent that is rare: Becoming a top tier talent in AI takes time. Being able to use off-the-self AI designed by other people is not enough to drive breakthrough 3 - The infrastructure hardware: Most importantly GPUs that are virtually all controlled by one US company, NVIDIA 4 - Electrical Power: Modern AI requires datacenter that consume astonishing amounts of electricity It is on these fronts that the big battles over AI supremacy and autonomy will be fought. Laying these pillars also highlights the dominance of the US: it is the first on every single one. The US has the top universities and AI companies. This Naturally translates to more talent available. The US has the only company capable of making high-end GPUs, and the US has the most electricity available. Other nations should wisely pick their battles and focus where they can make most impact. France for example, with it's nuclear energy and engineering culture could make it's mark, and Germany is already a leader in semiconductors. There is potential in Europe, the major question is will regulations and fiscal regimes adapt fast enough to allow for rapid technological growth. Even low and middle income countries could make a dent and enjoy the AI boom. Morocco is positioning itself as an electricity producer, and all countries could work on education and skill levels. The time where people had to leave the country to offer their services abroad is long gone. The internet has no borders, which also mean the brain drain does not need to happen! It's not impossible for a country to become a top tier exporter of high quality AI services. Again for it to happen, cross country work regulations, and exchange rate controls must be heavily simplified or completely removed. Final words, If anything the Deepseek story is interesting because it potentially expands the market for NVIDIA. If the story is true, it means that the market is now bigger, not smaller because lower grade GPUs have suddenly become more useful, without questioning the supremacy of the last generations of NVIDIA's AI workhorses.

The Billion-Dollar Question: How Much Is Your Data Worth in the Age of AI? Shapley Value in Data Economics 4598

In today’s AI-driven world, data is often compared to oil. However, not all data holds the same intrinsic value. While some datasets are critical for the performance of AI models, others contribute little or no enhancement. As organizations pour vast resources into acquiring, processing, and leveraging data, the ability to systematically assess its worth has become a fundamental challenge. **The Need for Intelligent Data Valuation** When companies acquire data, it’s not enough to simply consider its quantity. They must also evaluate its quality, uniqueness, and relevance to the problem at hand. Equally important is understanding the relationships between datasets—whether they complement each other or act as substitutes. This distinction plays a pivotal role in making cost-effective decisions. For example, a bank seeking to improve its fraud detection capabilities might consider purchasing two datasets: *-* **Transaction History (Dataset A): ** Records of past financial transactions, which may reveal patterns indicative of fraud. *- ***User Behavior Data (Dataset B): ** Behavioral analytics, such as login habits and spending behaviors, which can help identify anomalies. If combining both datasets leads to a significant improvement in fraud detection accuracy, they are considered complementary—together, they provide more value than the sum of their individual contributions. However, if one dataset alone offers nearly the same predictive power as the other, the second dataset becomes a substitute, diminishing its marginal value. This distinction is crucial. Companies can waste millions on redundant or low-value data if they fail to evaluate dataset interactions properly. A deeper understanding of these relationships helps ensure that only the most valuable data is acquired, processed, and used to drive AI-driven decision-making. **Assessing the True Economic Worth of Data with Shapley Value** To address this challenge, the **Shapley value**—a concept rooted in cooperative game theory—provides a fair and consistent method to assign value to datasets based on their contributions to the overall performance of an AI model. In this context, the "game" refers to model performance, and the "players" are the datasets used to train it. The Shapley value acts as a metric to evaluate the contribution of each dataset to the model’s performance. **General Concept of the Shapley Value** The Shapley value distributes the total "payoff" (or performance improvement) of a cooperative game (i.e., model accuracy) among the "players" (datasets) according to their marginal contributions. To calculate the Shapley value for a dataset, we consider all possible combinations of datasets and evaluate how much the addition of that particular dataset enhances the model’s performance. Let’s consider an example: Fraud Detection System: Imagine a fraud detection system with three datasets: *-* Transaction history (Dataset A) *-* User behavior data (Dataset B) *-* Geolocation data (Dataset C) To calculate the Shapley value, we would: 1. Evaluate the model’s performance with each dataset, both individually and in combinations 2. Determine the marginal contribution of each dataset by seeing how much it improves the model’s performance when added to the other datasets. 3. Calculate the average contribution of each dataset across all possible combinations. The Shapley value ensures that each dataset is credited according to its true contribution to enhancing the fraud detection system. This methodology evaluates the worth of data not only based on its individual impact but also by considering how it interacts with the other datasets.

Striking the perfect balance? Mastering academic demands while thriving in the personal life. 5459

With the hustle of academia, it’s very easy to focus only on what’s next—a looming deadline, the next exam, or an upcoming conference. Before you know it, those academic demands can creep into every corner of your life, making it tough to separate “work time” from “me time.” That’s why setting boundaries is so important. Whether it’s not answering emails after a certain hour or taking a proper lunch break, clear limits protect your mental health and nurture your relationships. Making Time for What Matters: One of the best ways to balance your academic workload with a fulfilling personal life is by using solid time management skills. It goes beyond just buying a planner—you have to create a realistic schedule, set achievable goals, and regularly check your progress. When you block out specific times for studying or research, it frees your mind to fully enjoy your personal pursuits later. For example, I started writing down all my meetings, and deadlines on a simple calendar, then penciled in “personal time” for reading, relaxing, or a quick break. Having those scheduled moments made it easier to focus on my tasks when it was actually “work time.” Learning to Say “No”: Another challenge I faced was learning to set limits with people around me. In the past, I’d say “yes” to every study group or committee meeting—leaving little space for rest. But saying “no” is sometimes the healthiest choice you can make. If a project isn’t urgent or a meeting doesn’t truly need your input, it’s okay to pass. By politely declining, you protect your mental health and keep your workload manageable. Small Breaks, Big Difference: Taking short breaks was also a lifesaver for me. Even a five-minute walk or a quick chat with a friend can recharge your brain, especially when you’re buried in readings or writing papers. When I tried to power through for hours without pausing, I ended up feeling overwhelmed and frustrated. Now, I schedule small breaks throughout my day. Celebrating Small Wins: Finally, I learned the power of celebrating small milestones. After finishing a tough chapter or hitting a key research goal, I give myself a little treat—like a coffee date with a friend or a short break. Recognizing these small wins reminds me that progress comes in steps, not leaps. It also keeps me motivated for the next challenge. By honoring each success, no matter how small, I stay positive and energized, even when juggling academic deadlines and personal responsibilities.

What I Learned in 2024 During My PhD (Beyond Academia) 6318

When people ask what I’ve learned during my PhD, they usually think it’s all about science—reading papers, running experiments, gathering data. But honestly? That’s barely 20% of what I’ve learned this past year. The real lessons have nothing to do with lab work. It’s more about how you plan. I’ve learned to pause, think things through, and focus on long-term goals. Not everything needs a fast answer, and not every problem needs to be fixed right away. The best decisions come when I keep my emotions in check and focus on strategy. Waiting is tough. Progress can be painfully slow. But I’ve learned that good things take time. Getting frustrated doesn’t help—staying calm does. Spending hours working alone makes you figure out who you really are—what motivates you, what stresses you out, and how much you can handle before you reach your limit. Some tasks felt pointless—reading papers I wasn’t excited about or presenting when I wasn’t ready—but those things made me better. The things I dreaded the most taught me the most. I’ve also realized that communication is about more than speaking—it’s about making people understand. Breaking down complex ideas is just as important as knowing them. How you explain things shapes how people see your work. And thinking critically isn’t just for science—it helps you understand the world better, question things, and spot what others might miss. I stopped waiting to feel “ready.” Confidence doesn’t come from knowing everything—it comes from showing up, trusting what you’ve learned, and getting better each time. I’ve also started thinking of my future like a game of chess—every move counts. Emotional decisions don’t last, but careful ones do. I’ve learned you can’t force your way through everything. Sometimes, you need to know when to speak, when to listen, and when to take a step back. Being diplomatic doesn’t mean you’re weak—it means you’re smart enough to handle things without making everything a fight. These lessons weren’t in any textbook. They came from real moments—the tough ones, the quiet ones, and the ones that felt overwhelming. It’s more than learning skills—it’s understanding yourself and becoming stronger with every step forward. Still, you don’t have to figure everything out alone. When you seek advice from someone who knows you and genuinely wants you to grow, you can skip some of the slow, painful steps. They help you see blind spots and make your process faster and smoother.

The origin(s) of Solutions 5195

Does it ever happen to you to be hit by a very deep question while enjoying you morning coffee? Each time it happens, I am here sharing that specific thought that probably emerged following the effect of caffeine. How do we think about solutions? Before thinking about this question, I feel that it’s a must to present its context in order to understand more my perspective. The day before, I wanted to stretch my brains neurons by trying to solve a puzzle, in other words a problem, a necessary element for the existence of solutions. The puzzle, or the problem I wanted to solve was a coding problem by LeetCode, in which I need to develop a code to recognize Palindrome numbers. Palindrome numbers possess the very unique property of being symmetric, meaning that you can read them from both sides. One famous example is 121, you can think of 1111, 2222, and the list goes on. The goal is not to dive in this amazing world land of Palindromes, perhaps we can do it later, but to illustrate an important point. I thought of two solutions, each one is relative to a different approach. I noticed that this applied to other problems too. I generally think of two types of solutions: 1) A domain knowledge based solution 2) A technical based solution The first category are solutions that come as a result of a domain expertise. Let’s take the example of the Palindrome numbers problem. One first reflex I had is to assess all mathematical properties that these numbers might have before putting my hands on the keyboard to translate those thoughts into code. The domain here is Mathematics, it could be any domain. One origin of solutions is the expertise ones gather through domain knowledge. This is what Data models try to imitate by capturing the hidden patterns given a set of features that are chosen, based on statistical measures yet they make sense from a domain knowledge point of view. The second category is relative to each domain. One easy way to recognize a Palindrome number is to convert it to a string, reverse it and then compare it with the original string. This is a technical solution brought up by the world of coding. Similar solutions exist in many domains, and if they are coupled with domain knowledge they can solve numerous problems. This type of solutions require the discipline’s domain knowledge which can be different from the problem’s domain knowledge, especially for a category of disciplines that are suppliers of tools (Coding, Statistics…). These two categories tell us about the origins of solutions. In every problem, there are two layers that we need to be aware of, the domain and the tool, both can offer a solution. A lot may argue that it’s not true in all cases, but we will assume it is possible to develop a solution following both methods, as numerous discoveries shape everyday reality and change the meaning of what is impossible. Quantum physics stun the world at their emergence, Information theory, and many other so called impossible things at a certain time. From a tool perspective, it is possible to merge tools that seems different yet they share a common point, no wonder why we see some domains interfering in many other domains like Data Science. Once we define clearly the roles of each layer it is possible to craft an ingenious solution to all problems, or we might end up realizing that we need to outsource an additional layer to help craft a more sophisticated solution that finds a way around the previous limitations. When I talk about origins, I place myself from a procedural perspective. This is one way to see it and not the only one. “ Genius Takes Time and Extraordinary Effort “

XR The Moroccan Association As An Intergenerational Lab : Giving Moroccan Children a Voice in Scientific Research 3566

SPARK (Scientific Project for Active Researchers Kids), which we have worked on for two years, holds a special place in our hearts. We believe that "good research is research with children rather than on children". As the first Moroccan intergenerational lab where children and adults are equal as active researchers, XR The Moroccan Association plays a significant role in bridging the "research divide" and reducing the generational "disconnect." Our experience shows that children are fully capable of developing their own ideas and collaborating within a cooperative inquiry group to understand their world and find practical solutions. XR The Moroccan Association believes that scientific research is not reserved for adults, but is a right for every Moroccan child, in alignment with Article 13 of the United Nations Convention on the Rights of the Child. The results speak for themselves: these children have published scientific articles on esteemed international platforms such as SCOPUS and Google Scholar. These publications are not just educational projects but address important, real-world issues, broadening their perspectives and boosting their self-confidence. They have also presented their work at renowned conferences held in Cambridge, India, and Washington, showcasing their research on an international stage. Through SPARK, we do not aim to create the best child researchers in the world but rather the best child researchers for the world. Our message today: science is a knowledge construct built on intergenerational exchange of ideas and collaboration. There are no valid reasons—and zero benefits—for restricting this expression in society. It is essential that all generations contribute to scientific research, as each age group brings valuable insights and experiences that enhance our understanding and innovation. By fostering this intergenerational exchange, we can create a richer, more inclusive scientific community that benefits everyone. The path to innovation is through intergenerational research cooperation! These efforts will culminate in a ceremony honoring the child researchers on November 16, 2024, at the Cultural Center Settat at 15:00 PM, in conjunction with International Day of Children’s Rights on November 20. This event will not only celebrate their achievements but also serve as a call to all to support this new generation of young scientists, encouraging more children to follow this path. For more information about articles by the child researchers: RAYAN FAIK : https://scholar.google.com/citations?user=8OqkR9MAAAAJ&hl=fr&oi=ao MISK SEHBANI : https://scholar.google.com/citations?user=5MwJX1YAAAAJ&hl=fr&oi=ao KHAWLA BETTACHI: https://scholar.google.com/citations?user=DJvyfQ0AAAAJ&hl=fr&oi=ao
xrm.ma/kids-researchers/

The future of AI: Originality gains more value 3538

With the spread of artificial intelligence and Large Language Models, everyone is wondering what the future looks like. Well, I'll tell you what it looks like. If today you made a post on LinkedIn or you wrote a book, or a research paper and you wrote it so well that it read as smooth as butter, and everyone could truly verify that it was originally written by you without the assistance of any AI like chatgpt, claude, gemini etc, then you would really be impressing a lot of people. That is what the future looks like to me. It is just like how the part of the population who can do math without calculators are considered geniuses in present times, whereas in the past it was either that or nothing.

Planetary magick and elementals 2649

In the wisdom of magickal traditions, the cosmos and the elements are seen as interconnected forces that shape the fabric of existence. Planetary Magick and the invocation of Elementals represent two halves of a greater whole—a harmonious interaction between the celestial and the terrestrial, the macrocosm and the microcosm. Through the alignment with planetary energies and the balance of elemental forces, the practitioner can unlock deeper wisdom, transformation, and spiritual power. At the core of Planetary Magick lies the understanding that the celestial bodies—Sun, Moon, and planets—are not merely distant physical objects but sources of spiritual energy, each resonating with specific archetypal forces. The Sun radiates vitality, leadership, and self-actualization, while Venus embodies love, harmony, and beauty. Mars burns with the fire of courage and conflict, while Mercury speeds communication and intellect. By invoking these planetary powers, the practitioner can channel their influence to enhance different areas of life, whether it be for personal empowerment, emotional healing, or intellectual clarity. Yet, the forces of the planets do not exist in isolation. They interact with and manifest through the Elementals, the spiritual entities that govern the four classical elements. Even the Fifth Element, Spirit, finds its place in this system. It is the element of transcendence, connecting material to the divine, much like the Sun, which illuminates the soul and gives life to all. Spirit represents the aether, the quintessence that binds all other elements, and through the Sun’s vitality, the practitioner integrates to their highest potential and spiritual purpose. Through rituals and meditations, the practitioner can harness both planetary and elemental forces, combining the expansive powers of the planets with the raw, natural energy of the elements. A ritual to invoke Venus for love and harmony might be strengthened by calling upon Water, for the undines can aid in deepening emotional bonds and fostering the flowing nature of relationships. Similarly, a working to harness Jupiter’s prosperity might be amplified by the stability and growth offered by Earth and its gnomes, grounding abundance in lasting form. The true art of magick lies in balance—understanding how the cosmic forces of the planets descend and manifest through the primal energies of the elements. By aligning with the planets, one learns to channel universal energies; by working with the elementals, one learns to direct these energies into practical, tangible outcomes. Together, Planetary Magick and the Elementals offer a powerful system for spiritual growth, transformation, and manifestation, teaching the practitioner how to live in harmony with both the heavens and the Earth. In uniting these two potent forces, the practitioner becomes both an alchemist of the soul and a magician of the cosmos, learning to navigate the expanse of celestial wisdom while grounding their will in the living world of nature. Whether invoking the fiery resolve of Mars through salamanders or seeking the deep emotional insight of the Moon through the undines, the combined forces of planetary and elemental magick serve as a pathway toward the mastery of both self and the universe.

Elemental beings 2095

In the ancient tradition of elemental manipulation, the relationship between humans and elemental beings is both mystical and deeply connected with the natural and metaphysical realms. These elementals, embodying the pure essence of fire, water, earth, and air, are more than just energy constructs—they are sentient beings with their own temperaments and personalities that reflect the elements they govern. Fire Elementals (Salamanders) are beings of passion, transformation, and destruction. They embody the unpredictable and volatile nature of fire, capable of both creating and consuming. Though feared for their destructive potential, they are also symbols of renewal, burning away the old to pave the way for the new. A skilled manipulator who bonds with a fire elemental can harness its power for creativity and inspiration. Water Elementals (Undines) mirror the fluid and ever-changing nature of water. They are empathetic beings, attuned to the emotional currents of those around them. Their dual nature reflects water’s capacity to be calm and healing, or forceful and destructive. Water elementals resonate with emotions such as sadness or tranquility and can be a source of peace or chaos depending on the manipulator's state of mind. Earth Elementals (Gnomes) are the embodiment of stability and endurance. Rooted in the foundation of the world, they represent the slow but unyielding forces of nature. These beings are protectors of the natural world, guarding forests, mountains, and caves, and are connected to the cycles of growth and decay. Their bond with a manipulator requires patience, as earth elementals do not easily bend to haste or change. Air Elementals (Sylphs) are ethereal beings of wind and storm, representing freedom, change, and the unseen currents of thought and inspiration. Elusive and playful, they are also capricious and unpredictable. Manipulators who form bonds with air elementals must embrace flexibility and creativity, as these beings resonate with those who are open-minded and innovative, but can be testing and fickle. The relationship between these elemental beings and aetherists is one of balance and respect. A true manipulator does not command elementals but forms a partnership with them. This bond is formed through attunement in the psychosphere, where the manipulator’s mind aligns with the elemental's essence. Emotional and mental harmony are key; any imbalance can disrupt the connection, leading to dire consequences. Elemental beings are far more likely to aid those who approach them with humility and respect for the natural forces they represent. This partnership reveals the broader truth that nature and mind are interconnected through the psychosphere, and through elemental manipulation, aetherists can harmonize with the primal forces that shape the world.

Servitors and golems 1277

Throughout history, humans have imagined and created artificial beings for a determined purpose and animated by will. Two classical examples of these constructs, from different cultural traditions, are servitors and golems. Both represent the human desire to give form to one's intentions, still they represent distinct philosophical and mystical ideas. Servitors are constructs created through mental or magical discipline, mainly within modern occult traditions. They are essentially thoughtforms, shaped from the mind’s energy and given a task or purpose by their creator. A servitor is bound by the will of its creator and exists to fulfill specific functions, such as protection, assistance, or manipulation of circumstances. The process of creating a servitor is a kind of psychic programming—the practitioner defines the servitor’s purpose, often assigning it a symbolic form or sigil to help channel its energy. Unlike physical constructs, servitors exist in the ethereal realm and are maintained by the energy and focus of their creator. Some belief systems deem that servitors can be “released” or “destroyed” once their purpose is fulfilled, ensuring they do not linger or develop independence. Servitors highlight the power of the mind to create and manifest reality through focus, belief, and willpower. On the other hand, golems come from Jewish mystical traditions, particularly Kabbalistic teachings. Unlike servitors, golems are physical constructs, typically made from inanimate materials like clay or stone. The most famous golem is the Golem of Prague, a figure created by Rabbi Judah Loew in the 16th century to protect the Jewish community from persecution. The golem is brought to life through ritualistic methods, often involving the inscription of sacred words or symbols, such as the Hebrew word “emet” (“truth”) on its forehead. These letters imbue the golem with life, while erasing the first letter (leaving “met,” or “death”) deactivates the golem. Golems are typically portrayed as powerful but mindless creatures, existing to carry out their creator’s commands without question. Unlike servitors, who may represent aspects of the creator’s mind, golems are more like automatons, lacking independent thought or will. Their power is derived from the ancient association between earth and life and once created, can become uncontrollable. While servitors are products of mental and magical discipline, golems represent the manipulation of physical matter through divine or mystical intervention. Servitors serve as an extension of the creator’s mental faculties, flexible and dynamic in their purpose. Golems, on the other hand, are a manifestation of physical creation, rigid and often prone to unintended consequences if not properly controlled. There are other forms of artificial beings which could be created. Franz Bardon, for example, gave us a few methods on how to create beings that could be qualified as in between the ones discussed in this text. Both servitors and golems reflect humanity’s ongoing fascination with the power of creation and the ways in which we might give life to our intentions. Whether through thought or clay, the desire to animate constructs reflects both a deep imagination and a cautionary tale about the limits of control over what we create.

Two Nobel Prizes: AI is Still resting on Giant Shoulders 1397

John Hopfield and Geoffrey Hinton got the Nobel Prize of Physics, Demis Hassabis and John Jumper the nobel Prize of Chemistry. It is obvious that the first Nobel Prize was not given merely for their contributions to physics, but mostly for their profound and foundational contributions to what is today modern AI. Let's talk about the second Nobel prize. AlphaFold was put on map by beating other methods on a competition (CASP14/CASP15) that has been running for year on a well established dataset. As such, AlphaFold winning is more like an ImageNet moment (when the team of Geof Hinton demonstrated the superiority of Convolutional Networks on Image Classification), than a triumph of multi-disciplinary AI research. The dataset of Alphafold rests on many years of slow and arduous research to compile a dataset in a format that could be understood not by machines, but by computer scientists. This massive problem of finding the protein structure was, through that humongous work, reduced to a simple question of minimizing distances. A problem that could now be tackled with little to no knowledge of chemistry, biology or proteomics. This in no way reduces the profond impact of AlphaFold. However it does highlight a major issue in applied AI: computer scientists, not AI, are still reliant on other disciplines to drastically simplify complex problems for them. The contributions and hard work required to do so gets unfortunately forgotten everything has been reduced to a dataset and a competition. What to do when we do not have problems that computer scientists can easily understand? This is true for all fields that require a very high level of domain knowledge. Through experience, I came to consider the pairing of AI specialists with specialists of other disciplines, a sub-optimal strategy at best. The Billions of dollars invested in such enterprises have failed to produce any significant return on investment. The number one blind spot of these endeavours is the supply chain, it usually takes years and looks like this: 1- Domain specialists identify a question 2- Years are spent to develop methods to measure and tackle it 3- The methods are made cheaper 4- The missing links: Computational chemists, Bioinformaticians, ... start the work on what will become the dataset 5- AI can finally enter the scene Point number (1) is the foundation. You can measure and ask an infinite number of questions about anything. Finding the most important one is not as obvious as it seems. For example, it is not at all obvious that a protein structure is an important feature a priory. Another example, is debugging code. A successful debugging session involves asking and answering a succession of relevant questions. Imagine giving a code to someone with no programming experience and asking them to debug it. The probabilities of them asking the right questions is very close to 0. Identifying what is important is called inserting inductive Biases. In theory LLMs could integrate the inductive biases of a field and generate interesting questions, even format datasets from open-source data. However until this ability has been fully demonstrated, the only cost efficient way to accelerate AI driven scientific discoveries is to build the disciplinarily into the people: AI Researchers that know enough about the field to be able to identify the relevant questions of the future.
nobelprize.org/all-nobel-prizes-...

Psychosphere and elemental manipulation 1705

For those attuned to the metaphysical plane called psychosphere, elemental manipulation becomes possible—a manifestation of willpower translated directly into physical reality. Fire, water, earth, and air are no longer inert forces of nature, but extensions of one's mental faculties. These elements, governed by their own natural laws, bend and respond to the psychic commands projected through the psychosphere. The flame dances with a mere thought, water ripples in time with a fleeting emotion, the earth trembles under the weight of a focused mind, and air bends and flows with each shift in consciousness. In ancient times, those who mastered this connection were known as aetherists, individuals who could sense the undercurrents of the psychosphere and use it as tool to commune with the elements. Aetherists were not simply powerful due to their abilities, but because of their profound understanding of how thoughts and emotions could influence their environment. The key to this manipulation is not found in brute strength, but in resonance. The psychosphere, like an ocean of thought and emotion, is sensitive to the subtlest shifts in energy. Those who can align their inner state—mind, heart, and spirit—with the it's flow, find themselves in harmony with the elemental forces. To manipulate fire, one must embody its intensity; to command water, one must flow with its rhythm; to bend air, a mind must be as light and agile as the breeze itself; to move the earth, one's will must be grounded, unshakable. As we can see, elemental manipulation is an intricate dance between mind and nature, mediated by the psychosphere. Each element responds to a specific emotional frequency: fire to passion, water to tranquility, air to freedom, and earth to stability. The most skilled practitioners are not merely wielders of power, but "symbiotic" partners with the elements, understanding that the psychosphere is both a reflection of their inner world and a gateway to controlling the outer one. Yet, the psychosphere is not a neutral space. As we discussed before, it is affected by the collective thoughts and emotions of all beings. Those who seek to manipulate elements must do so with caution, for the psychosphere is sensitive to the imbalances of mind and heart. A thought too aggressive might cause fire to rage uncontrollably; an unstable emotion might unleash a flood of water or shift tectonic plates with unintended force. Balance is key, and the psychosphere rewards those who seek harmony, not dominance, over the elements. Despite the potential for great power, the psychosphere is an inherently neutral force-it amplifies the intentions of the individual but does not judge them. this opens a moral dimension to elemental manipulation, as individuals can use their connection to the psychosphere for creation or destruction. In this world, where mind and matter intertwine, the psychosphere is the ultimate bridge between consciousness and the primal forces of nature. It is the invisible field where thoughts become actions, and the mastery of elemental manipulation is not merely a feat of mental prowess, but a journey toward inner equilibrium, a balance between the self and the world around it.

Egregores and the psychosphere 1485

The psychosphere can be understood as an energetic field that envelops the planet, serving as a living repository for the mental and emotional energies generated by all sentient beings. Some interpretations, such as those in the Gaia theory, even suggest that all emotional beings, including animals contribute to this field. For the sake of clarity in this discussion, I will focus solely on humans. The psychosphere exists as a subtle layer between the material world we inhabit and the higher, more ethereal planes, often referred to as the spiritual realm. Rich with thoughtforms—mental constructs born from individual or collective consciousness—it plays a determinant role in the astral plane. Though intangible to the physical senses, the psychosphere profoundly influences both individual experiences and the collective emotional state of humanity. At the core of the psychosphere are thoughtforms and egregores, which I discussed in my previous writing. These are the primary forces that shape this astral layer. Both thoughtforms and egregores contribute to the psychosphere, which grows denser with the energy they generate. While thoughtforms are personal and typically temporary, egregores have the potential to become enduring entities, sustained by the continual focus and intention of a group. These entities accumulate in the psychosphere, influencing the mental and emotional states of those who dwell within its planetary field. The psychosphere functions as a middle ground between the dense physical realm and the more subtle ethereal or spiritual planes. As a layer of the astral plane, its "matter" is finer than the physical world but denser than the purely spiritual realms. This gives it a unique role in the cosmological framework, acting as a bridge where mental energy and spiritual forces intersect, creating a dynamic interplay between human thought and extradimensional or spiritual influence. To provide a helpful metaphor, we can look to the superstring theory with its concept of multiple dimensions. Imagine the psychosphere as the "fine point" where different dimensions converge and interact, much like vibrating strings generate different forms of matter. The vibrations of thought and emotion within the psychosphere create and sustain various thoughtforms and egregores. These vibrations, in turn, shift and shape the energies of the astral plane, producing a vast and complex network of mental and spiritual activity. The astral plane, and by extension the psychosphere, influences human experience in subtle but powerful ways. On one hand, individuals and groups can shape the psychosphere through their focused intentions, emotions, and beliefs. On the other hand, the psychosphere exerts its influence on them, subtly affecting their thoughts, emotions, and behaviors. For example, when an egregore grows strong, it can exert pressure on the individuals who feed it. This can manifest as powerful collective emotions—such as national pride, religious fervor, or even mass hysteria. The egregore becomes a force that shapes the thoughts and behaviors of its creators, locking them into patterns of belief or action. This reciprocal relationship creates a feedback loop in which individuals both influence and are influenced by the larger thoughtform structures of the psychosphere. On a more personal level, the thoughtforms individuals generate can resonate within the psychosphere, attracting similar energies or influences from the astral plane. In some cases, these thoughtforms can be empowering, manifesting goals or desires in the physical world. In other instances, they may create unwanted energetic attachments or lingering emotional residues. Thoughtforms and egregores, like all things in the universe, have a lifespan. When the energy sustaining them wanes—due to a lack of focus, intention, or belief—they begin to dissolve. This dissolution is not always clean, however. Much like physical organisms, these entities can leave behind husks or residual energy patterns that linger in the psychosphere. These empty husks are a form of astral debris. Although they no longer possess the vibrancy or purpose they once had, they still exist as empty shells of what they once were. These remnants can be manipulated by beings on either side of the astral plane—whether from higher spiritual realms or lower astral dimensions. In the hands of malevolent or parasitic entities, these empty husks can be repurposed, filled with new energy, and used to influence or manipulate the emotions and thoughts of individuals. This can manifest as irrational fears, lingering emotional disturbances, or sudden shifts in consciousness. Conversely, benevolent entities may seek to dissipate or transform these husks into higher forms of energy, restoring balance within the psychosphere. The psychosphere is a dynamic, living field that reflects the collective mental and emotional states of the beings within it. It is influenced by human consciousness and, in turn, exerts its influence on the thoughts and emotions of those who interact with it. Through the creation of thoughtforms and egregores, individuals and groups shape the psychosphere, contributing to the intricate network of energetic patterns that govern the mental and spiritual landscape of the planet. The ongoing cycle of creation, sustenance, and dissolution of thoughtforms and egregores, shapes not only the psychosphere itself but also the experiences of those who live within its reach. Understanding this complex relationship allows us to better grasp how unseen forces may be influencing our inner and outer worlds, offering insights into the interconnectedness of mind, spirit, and the greater energetic realities that surround us.

Collective thoughtforms and their influence - egregores 1716

At the intersection of metaphysics, psychology, and collective experience lies the concept of egregores. These entities are, in essence, collective thoughtforms—mental and emotional constructs brought into existence and sustained by the shared focus, energy, and intent of a group of individuals. While a thoughtform arises from an individual’s sustained focus and emotional charge, taking on a life of its own in either the mental, astral, or sometimes even physical realms, an egregore is the result of a collective’s continuous input, becoming something far more potent and autonomous. Egregores start with shared ideas or emotions within a group. When people consistently focus on a common goal, these thoughts and emotions merge, forming an energetic presence that goes beyond the individual. The group may not be aware of this process, but over time, their collective energy manifests into a metaphysical structure, strengthened by rituals, symbols, and emotions. Symbols play a crucial role, serving as focal points for the group’s beliefs. Whether it’s a flag, logo, or chant, these symbols represent the group’s values, reinforcing the egregore’s existence. Every time individuals gather around these symbols, they contribute energy to the egregore. Once created, egregores can become autonomous, exerting influence on group members. Although born from the collective, they begin to act as independent entities, shaping thoughts, behaviors, and emotions. For instance, a religious community that collectively worships a deity may give rise to an egregore representing that deity. This egregore can influence how the group experiences their faith, guiding their actions and beliefs. In group dynamics, egregores enhance unity. Members may begin to share similar thoughts and actions, feeling connected to one another and their shared purpose. In emotionally charged situations, such as sports events, the collective energy can synchronize emotions across individuals, creating dramatic shifts and surges in group intensity. This collective energy often reaches peaks, amplifying shared experiences and reinforcing the bond within the group. The longer individuals are part of a group, the more their thoughts align with the egregore, amplifying its influence. Positively, this can lead to collective achievements, such as social movements or community growth. However, if the group’s energy centers on negative emotions like fear or hatred, the egregore can become destructive, influencing harmful actions. In modern contexts, egregores are reflected in brands, political ideologies, and social movements. For example, a brand like Apple may function as an egregore, where collective admiration and emotional investment shape customer behavior and company culture. Social media, too, serves as a powerful platform for the creation of egregores, amplifying collective thoughts and emotions. Online communities and viral trends generate intense focus, allowing egregores to influence large numbers of people quickly. Understanding egregores can empower individuals to consciously direct collective energy toward positive outcomes. By being mindful of shared thoughts and emotions, we can create egregores that foster unity, community, and collective success. Egregores ultimately remind us of the power of collective consciousness, which can shape both the inner and outer worlds of those who create them.

About symbols and sigils 1243

Symbols play a crucial role in our daily lives, shaping how we communicate and interpret the world around us. A symbol can be defined as an image, mark, or word that represents an object, concept, or abstraction. Carl Jung offers a profound exploration of this concept in his theory of aesthetics, emphasizing the psychological significance of symbols in our collective unconscious. Names are powerful symbols that engrave our identity in society. They carry personal history, culture, and meaning, helping us connect with others. Signatures serve a similar purpose, representing not just our names but also our intentions and agreements on various documents, from contracts to checks. Pins and passwords, too, can be viewed as symbols. They are abstractions we create to access personal or confidential information, representing trust and security in our digital interactions. Each type of symbol functions as a key to unlocking different facets of our identity and intentions. In essence, symbols can be categorized into two main types: disclosed and undisclosed. Disclosed symbols, like names and logos, are public and widely recognized, while undisclosed symbols, such as passwords and personal codes, are private and hold significance only for their creators. Sigils, a specific type of symbol, are often used in magical practices to invoke particular intentions or extradimensional entities. Traditionally, these symbols acted like a “telephone” to connect with these entities, serving as a means to channel one’s desires into the universe. In modern contexts, particularly within chaos magic, sigils are used to anchor one’s will to manifest specific goals, such as personal success or emotional healing. Interestingly, we encounter sigils daily, often without realizing it. Our names serve as disclosed sigils, necessary for identification in various activities—from registering for events to establishing online identities. Pins and passwords act as undisclosed sigils, known only to us and provide access to our personal digital realms, such as social media accounts or banking information. We are constantly surrounded by both created and absorbed sigils. From the brands we encounter to the symbols we personally create (like affirmations or vision boards), these sigils influence our thoughts and actions on both conscious and unconscious levels. Grant Morrison’s observation that "corporate sigils are super-breeders; they invade unbranded imaginative space" speaks to how commercial symbols can shape our desires and identities, often without our awareness. This brings us to a question: Do we unknowingly practice magick in our everyday lives? The rituals we perform—whether it’s setting intentions for the day or using symbols to navigate our environments—suggest that there may be more to our actions than mere routine. Ancient practitioners of magick often blurred the lines between what we now categorize as science and spiritual practice. They observed natural phenomena, conducted experiments, and created systems of understanding that predate modern scientific terminology. By examining the interplay between symbols, sigils, and our daily actions, we can appreciate the deeper meanings and influences that shape our lives. Symbols are not just marks or images; they are powerful tools that connect us to our identities, intentions, and the world around us.

Emotions and knowing oneself 1360

How can our emotions affect our thoughts and attitudes? That is easy to answer. We are emotional beings, and as such, many of us are guided by feelings rather than reason. For example, when someone annoys us, our immediate reaction is often frustration or anger. On the other hand, when someone treats us kindly, we typically feel gratitude and warmth. These emotional responses create a cycle in our daily lives that we often don't perceive. How can we start notice these patterns? Remember the "know thyself"? It is crucial. gaining a deeper understanding of ourselves is challenging, but it helps identify what triggers our strongest emotions and how we respond to them. By recognizing our emotional responses, we can take steps to manage, and eventually controlling, them and even transform our environment. A significant barrier to self-awareness is the masks we wear. Many of us tries to present a curated version of ourselves, shaped by cultural expectations and past experiences. This creates layers of "costumes" that can obscure our true identity. We often assert, "I am this" or "I am that", but have we truly examined who we are beneath those labels? We tend to showcase only our positive traits, hiding our flaws because they are seen as undesirable. It is essential to acknowledge that we all have imperfections. Rather than making excuses for our "dark side", we should recognize it and seek ways to improve. Just as we aim to enhance our strengths, we should also commit to learning from our challenges. The path to understanding our true selves -accepting both our strengths and weaknesses- guides us toward mastering our emotions. This self-awareness, along with a balanced self-acceptance (without justifying negative behaviors), enables us to respond more thoughtfully to the world around us. To conclude, here are three quotations that encapsulate my thoughts: - "Self-knowledge is the beginning of self-improvement." - Unknown - "Emotions are like waves. We can't stop the waves, but we can learn to surf." - Jon Kabat-Zinn - "The greatest discovery of my generation is that a human being can alter his life by altering his attitude". William James

Thoughts and co-creation 1234

There is an ancient knowledge that says - "all is mind, the universe is mental". This statement, if we think using a more theistic view, suggests that all things in the universe are a manifestation of a primordial thought, a primeval consciousness. To put it differently, there is a primary intelligence behind creation. As human beings we are part of this universe, this so-called creation. Given this premise, would it be wrong to assume that we could do the same? In other words, couldn't we be co-creators in this all? In my previous writing I discussed how we could use the principles of quantum physics to reshape our reality using our thoughts. Well, if all is mind, for sure we are co-creators! We already engage in co-creations every day. Through our thoughts we change the world when create art, to engineer new technologies, or express novel ideas. Could we take this further? Could we use our minds alone to modify the reality around us? I believe we can. Our minds don't think in words, these are mere abstractions created for communication. Instead, we think in images and mental pictures. For instance, when we feel thirsty, we don't simply think of the word "water" but envision a glass or a bottle. In other words, we use symbols to express our ideas. These symbols can be incredibly powerful in guiding and influencing us at every moment - just look at why companies invest so heavily in their logos and show them as much as they can. In summary, we think using symbols, and the most effective way to access them is through mental imagery or representations. Now, could we leverage these mental pictures and our concentrated will to alter the reality around us? Could our thought, when generated and guided with strong intention, be powerful enough to vibrate particles around us and initiate co-creations? We do that on a daily basis but, often unconsciously. "Know thyself" like some ancients advised, is the first step toward mastering our thoughts and consciously using them to our benefit.

Quantum Physics and our thoughts 1255

Quantum physics, one the most innovative fields of knowledge of modern science, tells us about a phenomenon known as the observer effect. It states that particles, in their potential state, do not have defined characteristics -such as movement or position- until they are observed. What implications does this have for our daily lives? Our conscious attention shapes the reality around us. When we focus on something, we align our thoughts and emotions with specific energies, influencing what we manifest into our lives. I guess a good analogy would be when are tuning into a radio station that is playing our favorite song. The problem is that it works when we have either positive or negative thoughts. The more we concentrate on something, the more the neural pathways associated with that thought become reinforced. Similarly, another intriguing concept found in quantum physics is the quantum entanglement, where two or more particles become linked in such a way that the state of one influence the state of another, independently of how far apart they are. With that information in mind, let's examine our thoughts. They are the result of several biochemical processes in our brains, which brings us to a question - Could it be that our thoughts or emotions impact the world around us? If so, is it possible we can influence reality simply through our thoughts? If the answer to both questions is yes, then could it be so far-fetched to think that we could use our will to change the environment for the better? I firmly believe we can! This phenomenon, known by many names - such as magnetism, mental power, faith or magick- invites us to recognize its existence. Quantum physics may provide, in my opinion, really good insights into its mechanisms. As an eccentric Englishman said once, "do what thou wilt...".

Why can't we accept other forms of science? 1283

What is science according to the "modern definition"? It would be the systematic study of the structure and behavior of the physical and natural world through observation, experimentation, and the testing of theories against the evidence obtained. Long and somewhat well put definition, however, there are sciences that could fit with the aforementioned explanation yet with some twists. One great example is metaphysics. What? Metaphysics?! Yes, indeed. The great problem with this "persecuted" and old science is the part where we cannot test it. What if say we can? Some will say that we can't test in a laboratory environment with our modern instruments and, because of this, it is untestable. I beg to differ. Several scientific phenomena we can test nowadays were untestable not so long ago. Some would say that they were metaphysical, even though they were observed. That brings me to the big question: why is the so called magick deemed as metaphysics? It happens, is observed and can be tested, however, not using the current technology. Or, isn't it? First, I think we should define what magick is. I guess we could say that is the practice of influencing events or outcomes through the power of one's will. Depending on who you ask the definition will be a different but, that's the most synthetic way I could define it. Of course there are several distinct schools and traditions of magick but it could be a topic for some other day. For now I just want to talk about some ideas. The superstring theory tells us that there is a possibility of several universes (a multiverse) and I would like to use it for a much smaller scale. What if, by the power of one's will we could make little portals within our own universe open? One would say that is only theory. What if I say that is has been done (on a huge scale!) by the scientific community, and it is right in front of our eyes? I won't say directly what it is now but I will give a hint - look at Switzerland, New York and California. I know that I still sound unconventional (even crazy) but it's only the beginning...

Learning Hypovolemic Shock in a Hard Way (or so I Thought) 1544

A few days ago, I suddenly felt cold after losing quite an amount of blood in the bathroom. I thought it was nothing unusual, but then I noticed the blood came out like water running down a faucet. I was not sure how much fluids I had lost, but a few seconds long was enough to know how bad it was. Before bed, I decided to search the web to satisfy my curiosity about my condition. Assuming to find common medical issues, I found out about a serious medical condition called "Hypovolemic Shock." The details are shocking and, without a doubt, mortified me. Thankfully my case was not severe (if not unrelated at all). I recovered in about 22 hours, although I had some headaches and numbness that went away by the next night. After recovering from the frightening experience, I was compelled to learn more about the condition, which led me to some surprising discoveries about hypovolemic shock. Disclaimer: This is just an overview of the topic I wrote for fun. If you want validation about your condition, please contact professional medical help. After reading several medical articles through the internet, I learned that hypovolemic shock is a serious condition caused by losing quite amount of blood or fluids within your body, and it is wise to quickly contact medical emergency as the condition poses a life-threatening risk. Hypovolemic shock can be divided to hemorrhagic and non-hemorrhagic type. Hemorrhagic shock happens when you lose fluids through serious blood loss, such as open wounds, internal bleeding, and childbirth. Meanwhile, non-hemorrhagic shock results from losing body fluids through other means, such as dehydration, diarrhea, and vomiting. Regardless of the difference, losing a lot of fluids can prevent the heart from sending blood through your body to function, which can lead to organ failure. Surprisingly, hypovolemic shock is the second most common shock, following distributive shock, and it commonly happens to children in developing countries, often due to diarrhea. Now, losing blood and other fluids is normal in everyday life without causing big side effect. Small losses, like from a small cut, nosebleed, or brief diarrhea, usually resolve on their own without causing bad effects. Generally, a person can lose about 14% of blood with no major side effects except perhaps for slight dizziness. And speaking of which, on average, men have more blood compared to women, while children, who have much less, are more vulnerable to the negative effects of blood loss. Since each individual has different amount of blood in them, it is important to measure the blood loss using percentage of the total blood volume in your body. One of the function of blood is to control body temperature (thermoregulation.) The body regulates the heat distribution by controlling the speed of the blood flow to and within the skin, either by narrowing or widening the blood vessels. When it is hot, the body widens the blood vessel (vasodilation) to cool down and release heat faster from the skin. Meanwhile, when it is cold, the body narrows the blood vessel (vasoconstriction) to keep the heat. When the amount of fluids is low, the body automatically narrows the blood vessels to keep the pressure normal and focus on distributing the blood to vital organs. What will happen when you lose more than 14% of blood? The quick answer is; you will start to experience the effect of blood loss. Depending on how fast you lose the fluids, you may feel tired and weak, with rapid breathing and pale skin, to more serious symptoms such as the decreased amount or no urine output, hypothermia, and unconsciousness. When the blood loss reaches more than 14%, hypovolemic shock will set in. Depending on how much blood percentage you have lost, hypovolemic shock can be separated into 4 stages: - The 1st stage: when you lose about 15% of your blood (around 750 mL.) At this stage, the symptoms have not occurred yet, and your heart rate and blood pressure may stay normal. - The 2nd stage: when you lose about 15% to 30% of your blood (around 750 mL to1,500 mL.) During this stage, the heart rate increases and breathing quickens as the blood vessels narrow to stabilize the pressure. - The 3rd stage: when you lose about 30% to 40% of your blood (around 1,500 mL to 2,000 mL.) At this stage, your blood pressure drops while your heart rate and breathing are getting faster. You begin to produce less to no urine output as the body tries to reserve the remaining fluids. - The 4th stage: when you lose about 40% or more of your blood (around 2,000 mL or more.) At this stage, your condition is at its critical and immediate professional attention provide slight survival chance. Your blood pressure is severely low, heart rate and breathing are high, urine output is absent, and organ failure is likely to happen and can become fatal. Hypovolemic shock is dangerous and needs immediate medical attention. In treating hypovolemic shock, medical help will try to replace the fluids you have lost using one or more IV (intravenous) lines, which is that long tube with a needle injected into your vein, and seal up the source of the fluid loss, such as open wound. Recovery time also takes some time and it is varied for each individual, depending on age, condition, and the severity of the shock. During recovery, you should listen to your health provider, and tell them your recovery progress so that they know your treatment goes to the right way. To sum it up, hypovolemic shock is a dangerous medical condition that we should never ignore, but understanding the signs can make a great difference. When blood or fluids loss persists longer than it should, contacting medical help can prevent unwanted experience to happen. And for my experience, I am grateful that my condition was not that alarming to demand me get out of bed in the middle of the night and call for an ambulance. This event, however, became a warning to keep an eye on my fiber intake more carefully and how important it is to take care of myself. For now, it is safe to say that I have survived my recklessness and ignorance for another day. Cheers. -Silver-

What’s All This Buzz About Monkeypox? 1344

Everyone’s talking about it. Monkeypox. It’s all over the news, and people are scared. But what is it, really? Should we be worried, or is this just another overhyped health scare? Monkeypox isn’t something new. It was first identified in 1958 in monkeys, which is how it got its name, but the first human case was recorded in 1970 in the Democratic Republic of the Congo. For decades, it remained mostly confined to Central and West Africa, with only occasional cases elsewhere. But now, it’s spreading faster and wider than before. That’s why it’s making headlines and causing concern globally. Let’s be clear: monkeypox is not COVID-19. It spreads differently, and it’s generally less contagious. But it can still be serious, especially for certain groups like young children, pregnant women, and those with weakened immune systems. So, how does one catch monkeypox? Mainly through close contact with an infected person or animal. This could mean direct skin-to-skin contact, being exposed to respiratory droplets, or touching contaminated objects like bedding or clothing. Unlike COVID-19, which can spread through the air over distances, monkeypox requires more direct contact. The symptoms can be unsettling. It usually starts with flu-like symptoms — fever, headaches, muscle aches, and swollen lymph nodes. Then, within a few days, a distinctive rash develops, often beginning on the face and then spreading to other parts of the body. These rashes turn into raised bumps that eventually fill with fluid, becoming painful blisters. In some cases, these lesions can leave scars. Despite these symptoms, most people recover within two to four weeks without the need for serious medical intervention. But complications can occur, especially in those with underlying health conditions. Here’s the silver lining: there are vaccines. If you’ve been vaccinated against smallpox, you might already have some level of protection against monkeypox. This is because the viruses that cause smallpox and monkeypox are closely related. In fact, the smallpox vaccine has been shown to be about 85% effective in preventing monkeypox. For those without prior vaccination, newer vaccines specifically targeting monkeypox are now available. Now, let’s talk about the bigger picture. The resurgence of monkeypox outside of Africa raises questions about how well-prepared we are for emerging infectious diseases. With increased travel and global interconnectedness, diseases that were once localized can spread quickly across borders. This situation reminds us of the importance of strong public health systems and the need for global cooperation in disease surveillance and response. But let’s not panic. Monkeypox is serious, but it’s also manageable with the right precautions. For more detailed information, check out WHO’s page on monkeypox. So yes, monkeypox is something to be aware of, but with the right knowledge and precautions, there’s no need to panic. Stay safe, stay smart, and keep looking out for each other.
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You Graduated and Don’t Know What to Focus On for a PhD Position? 1483

I assume you’ve just earned your master’s degree. You might be feeling a bit lost. You’ve started applying for opportunities — Industry or Academia — but you’re still waiting for that interview opportunity. No one is answering your emails. I get it. You might be feeling frustrated, maybe even battling imposter syndrome. You’re thinking about enrolling in new courses to acquire enough skills to be ready for any opportunity, but you still feel very lost. Let me tell you exactly what I would do if I were in your place three years ago. Please read this article until the end. You will enjoy it, and I made it especially for you as a source of motivation, giving you exactly what you should focus on. Let’s assume first that you want to enroll in a good PhD program. Whenever I apply for an opportunity, I put myself in the interviewer’s shoes — in this case, your future supervisor. What does your future supervisor want from you? What’s your added value to their lab? Why should they recruit you? Your supervisor wants you to be the greatest version of yourself, wants to be proud of you, and wants your success to be their success as well. First, they want you to avoid distractions and focus on your PhD, producing great, interesting results, and discoveries that lead to high-quality publications. They want you to step out of your comfort zone, present at international conferences, bring added value to the lab, be a great representative, and never outshine them. Control your ego, be easygoing with the team — not a toxic presence — and remember, they don’t expect perfection, but they do expect you to do your best. I know you can be like that, but there are a few things you can do to make your application stand out. When writing emails to potential supervisors, have you read some of their most interesting, highly cited articles? Did you do some research beforehand and address specific points within your email? What did you accomplish during your master’s degree? Were you just an average student who passed exams, or did you do something exceptional that made you unique compared to most students? If yes, then mention it, talk about it, and sell it to your supervisor in your application. Show that you are unique. When writing an email, motivation letter, or research proposal, stop using templates or AI-generated content. Your supervisor is smarter than you think, and they will spot that because they’ve seen a ton of applications. They want originality; they want to know who you are and what you can do. Be original. You don’t have to make it perfect, just be yourself. I want you to create a unique application that will impress any professor who reads it. Make it stand out. Use your own creativity — you’ve graduated, which means your brain is still fresh, and you are smart. SHOW THEM THAT! Don’t apply for just one position — make different plans. You gotta be smart about it. Reach out to your previous professors, especially those whose work you found impressive, and gently ask them for a recommendation letter. Use your contacts, and take your time to make different plans, because this step is a big one toward your future goals. Be wise about it. This isn’t just about getting one position; it’s about setting up a foundation for your future. Different plans give you options, and options give you control over your path. Last but not least, if I were you, I would focus on reading a bunch of review papers in the field I’m interested in. Start doing the things your future supervisor would expect you to do in your first year: identify the scientific question that interests you, find your unique approach, and start working on answering it. It’s your mission to find the gap in your field and fill it. You can begin working on that right now, while also doing the things I mentioned above. I’m not going to dig into the details here because I’ve kept this article a bit general, but if you have any questions, feel free to ask them directly.

Is PhD for you or not? 1787

Why is a PhD so tough? If I still get the chance to do a PhD, should I still consider doing it? I get plenty of questions asking me, “Why should I apply for a PhD? What are the benefits? Where, in what field, and with which supervisor should I consider doing it?” I will answer all these common questions in this article and give a few pieces of advice for graduate students and anyone hesitating to enroll in a PhD program. First things first, if you ask any PhD candidate or someone with a PhD about their experience, we all share the same answer: “PhD is tough.” But why? A PhD program is meant to shape you personally and professionally. It’s a minimum of three years where you discover your weaknesses, build a strong foundation of expertise, focus, and social dynamics, and it takes you out of your comfort zone. I’ll explain everything in detail with examples. The idea I had about a PhD when I recently graduated is completely different from what I am experiencing right now. Before, I thought a PhD program was all about publishing papers, and back then, for me, a paper could be done in less than four months. I mean, indeed, but that’s only for a mediocre paper with no impact, which could be published in a normal to predatory journal. Now I realize that publishing a high-quality article takes years of hard work, consistency, collaboration with a team of experts, making mistakes, conducting experiments, re-conducting experiments, taking critical advice from your supervisors, and implementing it effectively. Even then, you may or may not get the expected results. You may feel frustrated and get a bit depressed since you spent at least a year working on an approach that now seems no longer promising. That’s one side. The other side is psychology. What I mean by that is how you can feel really down, but regardless of your feelings, you discover your passion that can boost you and give you the purpose to balance your PhD and personal life. Then there is a critical aspect, which is your supervisor. You and your supervisor are two different people. Your supervisor has more experience than you, and as you’re conducting your PhD, doing the experiments, once you get critical feedback from your supervisor, you may take it personally and start thinking negatively about your experience, assuming he’s not helping you but just criticizing your work. That’s not true. What you actually learn about a PhD is that your supervisor’s success is yours as well, and vice versa. Since he has more experience than you in publishing high-quality articles, you should definitely forget about your ego, start communicating with him, and learn from him, because at the end of the day, you are still a student, and that’s what’s great about the PhD experience. Besides publishing, which is just a small part of your PhD program, you learn how to communicate your research area and results in a smooth way that anyone with a different background, or even a 5-year-old kid, could understand. You also learn how to sell your research, which means that you can definitely be a great candidate for the industry in the future, not just academia. Public speaking is another important skill you learn in a PhD since it is required to present your work at international conferences and congresses in front of highly valued speakers. You start to appreciate criticism and see it as a new way to improve yourself. If your primary goal is to improve yourself, be self-aware, and be better, then a PhD program is for you. If you are not, just forget about a PhD program because you will struggle, start comparing yourself with others, or may stop comparing yourself with others in a bad way that may lead you to become a narcissistic psychopath who thinks his PhD thesis is going to change the world and that everything he does is what matters, while what others do is completely irrelevant. At the end of the day, a PhD program is just a way to reach your higher goals, and if you see it as it’s supposed to be, then you’re going to have an enjoyable experience, full of learning, and enjoy science as it’s supposed to be. My Advice for Future PhD Candidates: - Your Supervisor: The first thing you should look for is your supervisor rather than the subject of your thesis. Your supervisor is the one you will be working with every single day for at least four years. He should be a good human being, skilled, and inspirational because their words can be a great motivation for you. Otherwise, if not, your experience is just going to get worse and worse, and you may quit. - Self-Improvement: Consider if you really want to improve your weaknesses and become a better version of yourself. Are you ready for high criticism of work that you spent years on? Would you accept that? If yes, then go for a PhD. - Academia: Academia is super toxic. Are you ready to engage in what might be a toxic environment and learn how to get the good side from it? If yes, then trust me, you will be perfectly shaped after your PhD, and you will be a great fit for both academia and industry. - Financial Goals: If your goal is to get money rather than improving yourself, just forget about academia because it will simply slow down that process of getting money as soon as possible. ---- To answer the first question, if I get the chance to start my PhD with the same conditions, the same supervisor, and the same thesis director, I would definitely follow the same path. Hell yeah, I love it!
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Snake Venom That Does Nothing to a Honey Badger, Kills a Human 2155

The honey badger is one of nature's toughest creatures. Despite its small size, this fearless animal isn't afraid to take on some of the most dangerous predators, including venomous snakes. What’s truly fascinating is that the snake venom that can kill a human has little effect on a honey badger---- The honey badger, also called a ratel, lives in Africa, Southwest Asia, and parts of India. It’s known for its aggressive behavior, strong build, and thick, loose skin, which makes it hard for snake fangs to deliver a full dose of venom. This tough skin is one reason why honey badgers can survive snake bites that would be deadly to other animals. ---- But the honey badger's resistance to venom isn't just about its skin. Scientists have discovered that honey badgers have special adaptations at the molecular level. Snake venom typically attacks nerve cells by binding to specific receptors. However, the honey badger's receptors have evolved to be less affected by these toxins, allowing the badger to survive bites that would be fatal to humans. ---- Another interesting aspect is how honey badgers react when bitten. They might show signs of being affected by the venom, such as slowing down or swelling, but they often recover quickly. This suggests that their bodies have proteins or other molecules that neutralize the venom, helping them bounce back after an encounter with a deadly snake. FASCINATING, right?

Can You Become a Millionaire by Working on Venom? Yes! 1437

The idea of becoming a millionaire might conjure images of tech startups, real estate investments, or Wall Street. But working with venom can be your ticket to wealth, thanks to its significant medical and commercial potential. ---- Venom, produced by creatures like snakes, spiders, and scorpions, is a complex mixture of proteins and peptides. These toxic cocktails hold incredible potential for medical applications, creating a profitable intersection of nature and science.---- Venom-derived drugs have made significant impacts in medicine. For instance: - Captopril, derived from the Brazilian pit viper's venom, generates over $1 billion annually in revenue. - Prialt, a painkiller from cone snail venom, can cost up to $20,000 per year per patient. ---- The pharmaceutical industry constantly seeks new compounds for effective treatments. Venom-derived substances are particularly appealing, leading to substantial investments in research and development. This can result in lucrative patents and partnerships.---- Venom production and farming are other profitable ventures. Companies like Amsaal Venom Farm LLC specialize in producing and distributing venom for research and antivenom production. High-quality venom can sell for up to $5,000 per gram, depending on the species and purity.---- Owning patents on venom-derived compounds is highly lucrative. Licensing these patents to pharmaceutical companies can yield substantial royalty payments. For example, licensing agreements typically offer 3–5% royalties on net sales. A successful drug generating $500 million annually could provide $15-$25 million in royalties.---- Imagine discovering a new venom-derived compound that becomes a best-selling drug. With an annual revenue of $1 billion and a 3% royalty, you could earn $30 million per year. Alternatively, running a venom farm producing 100 grams of high-quality venom per year could generate $500,000 annually, assuming a $5,000 per gram price.

How Nature's Deadliest Creatures Influence Medicines? 1222

When we think about the most dangerous animals in the world, we often imagine deadly snakes, venomous spiders, or stinging scorpions. These creatures are feared for their powerful venoms, but what if I told you that their venoms could save lives? It may sound surprising, but many scientists are now using these dangerous venoms to create new medicines. Here are some of my thoughts on this fascinating topic. Spider venom might give you chills, but it is also giving hope to people who suffer from strokes. The Australian funnel-web spider (Atrax robustus) produces a venom that contains a peptide called Hi1a. This peptide has been found to protect brain cells from damage caused by a stroke. Researchers are studying Hi1a to create treatments that could save the lives of stroke victims and help them recover more quickly. Snakes are some of the most feared animals on the planet, but their venom is helping to treat serious illnesses. For example, the Brazilian pit viper (Bothrops jararaca) produces a venom that contains a molecule called bradykinin-potentiating peptide (BPP). This molecule has been used to develop a class of drugs known as ACE inhibitors, which are commonly prescribed to treat high blood pressure and heart failure. These drugs work by relaxing blood vessels and reducing blood pressure, turning a deadly venom into a lifesaving medication. Scorpion venom is another powerful substance that is being turned into medicine. Researchers have found that a protein in scorpion venom, chlorotoxin, can bind specifically to cancer cells without affecting healthy cells. This discovery has led to the development of a drug called Tumor Paint, which helps surgeons see cancer cells more clearly during surgery. The venom of the deathstalker scorpion (Leiurus quinquestriatus) is being harnessed to ensure that cancerous tissue is removed more precisely, reducing the risk of recurrence. The ocean is home to many venomous creatures, like cone snails and jellyfish. The venom of the cone snail (Conus magus) contains a compound called ziconotide, which has been developed into a drug for severe chronic pain. Ziconotide works by blocking calcium channels in nerve cells, preventing pain signals from reaching the brain. This non-opioid painkiller offers a powerful alternative to traditional pain medications and has been a significant breakthrough in pain management. Bees and wasps are often seen as pests, but their venoms are being used to help treat autoimmune diseases. Melittin, a peptide found in bee venom, has shown potential in treating conditions like multiple sclerosis and rheumatoid arthritis. Melittin can modulate the immune response and reduce inflammation. Scientists are working to isolate and modify melittin to enhance its therapeutic effects while minimizing side effects, offering new hope to patients with these challenging conditions. The Gila monster is a venomous lizard whose saliva contains a hormone called exendin-4. This hormone has been turned into a drug called exenatide, which helps people with type 2 diabetes manage their blood sugar levels. Exenatide mimics the action of a natural hormone that stimulates insulin release and inhibits glucagon production, effectively controlling blood glucose levels. It's amazing to think that a substance from a lizard's mouth can help millions of people control their diabetes. Centipedes might seem like creepy crawlies, but their venom is showing promise as a pain reliever. The venom of the Chinese red-headed centipede (Scolopendra subspinipes mutilans) contains a peptide called SsTx. SsTx can block pain signals by inhibiting sodium channels in nerve cells, offering a new approach to pain management. Researchers are synthesizing SsTx in the lab and conducting trials to evaluate its effectiveness and safety, potentially leading to new, non-addictive painkillers. It is truly fascinating how scientists can transform deadly venoms into life-saving medicines. Studying these natural toxins, researchers are finding new ways to treat some of the most challenging diseases and conditions. This innovation shows the incredible diversity of nature and emphasizes the importance of preserving these species and their habitats. The transformation from venom to cure is a remarkable testament to human ingenuity and the power of nature. Attached, please find our open-source scientific article explaining everything in detail.
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